Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR3 | P32745 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 5/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | XBP1 | P17861 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | JAK2 | O60674 | 3/20 | 0.48 |
| ▸ | PTPRB | P23467 | 2/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1197175 | 1.00 | SSTR3 (0.55) | SSTR3ALDH1A1HPGDHTTNPSR1 | |
| SCHEMBL22060193 | 0.88 | SSTR3 (0.54) | SSTR3ALDH1A1HPGDHTTNPSR1 | |
| SCHEMBL1197108 | 0.88 | SSTR3 (0.54) | SSTR3ALDH1A1HPGDHTTNPSR1 | |
| SCHEMBL20630809 | 0.86 | SSTR3 (0.52) | SSTR3ALDH1A1HPGDHTTNPSR1 | |
| SCHEMBL390451 | 0.86 | SSTR3 (0.52) | SSTR3ALDH1A1HPGDHTTNPSR1 | |
| SCHEMBL20630526 | 0.85 | SSTR3 (0.52) | SSTR3ALDH1A1HPGDHTTNPSR1 | |
| SCHEMBL1197182 | 0.81 | ALDH1A1 (0.52) | SSTR3ALDH1A1HPGDHTTNPSR1 | |
| SCHEMBL15875597 | 0.81 | ALDH1A1 (0.52) | SSTR3ALDH1A1HPGDHTTNPSR1 | |
| SCHEMBL1197116 | 0.80 | ALDH1A1 (0.49) | SSTR3ALDH1A1HPGDHTTNPSR1 | |
| SCHEMBL6791477 | 0.79 | ALDH1A1 (0.58) | ALDH1A1HPGDHTTNPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981854-A1 | ARYLPROPIONAMIDE, ARYLACRYLAMIDE, ARYLPROPYNAMIDE, OR ARYLMETHYLUREA ANALOGS AS FACTOR XIA INHIBITORS | Brystol-Myers Squibb Company (US) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007070826-A1 | ARYLPROPIONAMIDE, ARYLACRYLAMIDE, ARYLPROPYNAMIDE, OR ARYLMETHYLUREA ANALOGS AS FACTOR XIA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-06-21 | — | — | WO | disclosed |