Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 7/20 | 0.59 |
| ▸ | PTPN7 | P35236 | 5/20 | 0.59 |
| ▸ | SELP | P16109 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8761928 | 1.00 | HMGCR (0.59) | HMGCRPTPN7SELPRECQLTDP1 | |
| SCHEMBL10464578 | 0.98 | HMGCR (0.58) | HMGCRPTPN7SELPRECQLTDP1 | |
| SCHEMBL7623766 | 0.86 | PTPN7 (0.53) | HMGCRPTPN7SELPRECQLTDP1 | |
| SCHEMBL28658232 | 0.86 | PTPN7 (0.53) | HMGCRPTPN7SELPRECQLTDP1 | |
| SCHEMBL1198893 | 0.84 | PTPN7 (0.50) | HMGCRPTPN7SELPRECQLTDP1 | |
| SCHEMBL414528 | 0.82 | HMGCR (0.67) | HMGCRPTPN7SELPRECQLTDP1 | |
| SCHEMBL1540252 | 0.82 | HMGCR (0.67) | HMGCRPTPN7SELPRECQLTDP1 | |
| SCHEMBL1933871 | 0.82 | HMGCR (0.67) | HMGCRPTPN7SELPRECQLTDP1 | |
| SCHEMBL2553337 | 0.82 | HMGCR (0.67) | HMGCRPTPN7SELPRECQLTDP1 | |
| SCHEMBL4225757 | 0.82 | HMGCR (0.72) | HMGCRPTPN7SELPRECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7399977-B2 | Apparatus and method for determining radiation dose | UNIVERSITY HEALTH NETWORK (CA) | 2008-07-15 | — | — | US | disclosed |
| US-20060017009-A1 | Apparatus and method for determining radiation dose | UNIVERSITY HEALTH NETWORK (CA) | 2006-01-26 | — | — | US | disclosed |