Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 8/20 | 0.55 |
| ▸ | AVPR1A | P37288 | 6/20 | 0.51 |
| ▸ | AVPR2 | P30518 | 5/20 | 0.51 |
| ▸ | OXTR | P30559 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4866989 | 0.83 | TSHR (0.71) | AVPR1AAVPR2OXTRTSHR | |
| SCHEMBL4867001 | 0.83 | TSHR (0.71) | AVPR1AAVPR2OXTRTSHR | |
| SCHEMBL4870436 | 0.83 | TSHR (0.71) | AVPR1AAVPR2OXTRTSHR | |
| SCHEMBL1858662 | 0.79 | HSD11B1 (0.61) | HSD11B1TSHR | |
| SCHEMBL5421718 | 0.79 | HSD11B1 (0.78) | HSD11B1TSHR | |
| SCHEMBL4867650 | 0.79 | AVPR2 (0.62) | HSD11B1AVPR1AAVPR2OXTR | |
| SCHEMBL16448032 | 0.76 | HSD11B1 (0.57) | HSD11B1TSHR | |
| SCHEMBL8641006 | 0.75 | NPC1 (0.46) | — | |
| SCHEMBL28508464 | 0.74 | NOTUM (0.62) | TSHR | |
| SCHEMBL4867471 | 0.74 | TP53 (0.81) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7368444-B2 | N-carbamoyl nitrogen-containing fused ring compounds and drugs containing these compounds as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-05-06 | — | — | US | disclosed |
| US-20050101600-A1 | N-carbamoyl nitrogen-containing fused ring compounds and drugs containing these compounds as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | US | disclosed |
| EP-1475368-A1 | N-CARBAMOYL NITROGEN-CONTAINING FUSED RING COMPOUNDS AND DRUGS CONTAINING THESE COMPOUNDS AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-11-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050101600-A1 | N-carbamoyl nitrogen-containing fused ring compounds and drugs containing these compounds as the active ingredient | CNR1, CNR2, NPSR1 | HSD11B1 365/4885AVPR1A 276/4885AVPR2 124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.