SCHEMBL4866178

SCHEMBL4866178

CC=CCC(=O)C(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2932014 1.00
SCHEMBL28034175 0.97 OR51E2 (0.38)
SCHEMBL3505065 0.78
SCHEMBL3505066 0.78
SCHEMBL8943586 0.78 ALDH1A1 (0.36)
SCHEMBL34656 0.77
SCHEMBL360177 0.77
SCHEMBL34657 0.77
SCHEMBL9225657 0.77
SCHEMBL8181223 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1844022-B1 QUINAZOLINE DERIVATIVES FOR INHIBITING CANCER CELL GROWTH AND METHOD FOR THE PREPARATION THEREOF HANMI SCIENCE CO LTD (KR) 2013-08-14 EP claimed
JP-2008525522-A 2008-07-17 JP claimed
US-20080009509-A1 Quinazoline Derivatives For Inhibiting Cancer Cell Growth And Method For The Preparation Thereof HANMI PHARM CO., LTD (KR) 2008-01-10 US claimed
EP-1844022-A1 QUINAZOLINE DERIVATIVES FOR INHIBITING CANCER CELL GROWTH AND METHOD FOR THE PREPARATION THEREOF Hanmi Pharm. Co., Ltd. (KR) 2007-10-17 EP claimed
WO-2006071017-A1 QUINAZOLINE DERIVATIVES FOR INHIBITING CANCER CELL GROWTH AND METHOD FOR THE PREPARATION THEREOF HANMI PHARM. CO., LTD. (KR) 2006-07-06 WO claimed
US-9345997-B2 Active polymeric filters EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2016-05-24 US disclosed
US-20130317178-A1 ACTIVE POLYMERIC FILTERS EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2013-11-28 US disclosed
US-8524920-B2 Active polymeric filters EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2013-09-03 US disclosed
US-8524919-B2 Active polymeric filters EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2013-09-03 US disclosed
EP-1844022-B1 QUINAZOLINE DERIVATIVES FOR INHIBITING CANCER CELL GROWTH AND METHOD FOR THE PREPARATION THEREOF HANMI SCIENCE CO LTD (KR) 2013-08-14 EP disclosed
WO-2013058736-A1 ACTIVE POLYMERIC FILTERS COMPRISING PENDANT DIOXIRANES EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2013-04-25 WO disclosed
US-20130092638-A1 ACTIVE POLYMERIC FILTERS CRESTLINE DIRECT FINANCE, L.P. 2013-04-18 US disclosed
EP-1844022-A1 QUINAZOLINE DERIVATIVES FOR INHIBITING CANCER CELL GROWTH AND METHOD FOR THE PREPARATION THEREOF Hanmi Pharm. Co., Ltd. (KR) 2007-10-17 EP disclosed
US-7087797-B2 Continuous hydroformylation process DSM IP ASSETS B.V. (NL) 2006-08-08 US disclosed
WO-2006071017-A1 QUINAZOLINE DERIVATIVES FOR INHIBITING CANCER CELL GROWTH AND METHOD FOR THE PREPARATION THEREOF HANMI PHARM. CO., LTD. (KR) 2006-07-06 WO disclosed
US-20040152924-A1 Continuous hydroformylation process DSM I.P. ASSETS B.V. (NL) 2004-08-05 US disclosed
EP-1392633-A1 CONTINUOUS HYDROFORMYLATION PROCESS DSM IP Assets B.V. (NL) 2004-03-03 EP disclosed
WO-2002083613-A1 CONTINUOUS HYDROFORMYLATION PROCESS DSM IP ASSETS B.V. (NL) 2002-10-24 WO disclosed
EP-1249439-A1 Continuous hydroformylation process DSM N.V. (NL) 2002-10-16 EP disclosed
EP-1249441-A1 Continuous hydroformylation process DSM N.V. (NL) 2002-10-16 EP disclosed