SCHEMBL4866294

SCHEMBL4866294

O=C(CC1CCCC1)Nc1ccccc1

nearest known ligand 0.97

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 4/20 0.97
NPC1 O15118 4/20 0.73
RAB9A P51151 4/20 0.73
KMT2A Q03164 3/20 0.73
TDP1 Q9NUW8 1/20 0.66
NAMPT P43490 2/20 0.65
TSHR P16473 1/20 0.61
EPHX1 P07099 1/20 0.59
CYP1A2 P05177 1/20 0.59
CYP3A4 P08684 1/20 0.59
CYP2D6 P10635 1/20 0.59
HPGD P15428 1/20 0.59
CYP2C19 P33261 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
KLK7 P49862 1/20 0.58
IDO1 P14902 1/20 0.58
MEN1 O00255 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3822162 0.98 EPHX2 (1.00) EPHX2NPC1RAB9AKMT2ATDP1
SCHEMBL26154069 0.96 EPHX2 (0.90) EPHX2NPC1RAB9AKMT2ATDP1
SCHEMBL11208728 0.93 EPHX2 (0.83) EPHX2NPC1RAB9AKMT2ATDP1
SCHEMBL3453739 0.85 EPHX2 (0.71) EPHX2NPC1RAB9AKMT2ATDP1
SCHEMBL29923548 0.85 EPHX2 (0.71) EPHX2NPC1RAB9AKMT2ATDP1
SCHEMBL15376346 0.85 EPHX2 (0.71) EPHX2NPC1RAB9AKMT2ATDP1
SCHEMBL3824111 0.84 EPHX2 (0.70) EPHX2NPC1RAB9AKMT2ATDP1
SCHEMBL17737334 0.83 IDO1 (0.82) EPHX2NPC1RAB9AKMT2ATDP1
SCHEMBL20838748 0.83 IDO1 (0.82) EPHX2NPC1RAB9AKMT2ATDP1
Hydrochloric Acid SCHEMBL6522503 0.83 EPHX2 (0.69) EPHX2NPC1RAB9AKMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200385558-A1 RESIN COMPOSITION, OPTICAL FILTER, IMAGE DISPLAY DEVICE, SOLID-STATE IMAGING ELEMENT, AND COMPOUND FUJIFILM CORPORATION (JP) 2020-12-10 US disclosed
US-20080153917-A1 Sigma Receptor Ligands UCB PHARMA, S.A. (BE) 2008-06-26 US disclosed
US-20080153917-A1 Sigma Receptor Ligands UCB PHARMA, S.A. (BE) 2008-06-26 US disclosed
EP-1797036-A1 SIGMA RECEPTOR LIGANDS UCB Pharma, S.A. (BE) 2007-06-20 EP disclosed
EP-1797036-A1 SIGMA RECEPTOR LIGANDS UCB Pharma, S.A. (BE) 2007-06-20 EP disclosed
WO-2006027252-A1 SIGMA RECEPTOR LIGANDS UCB PHARMA, SA (BE) 2006-03-16 WO disclosed
WO-2006027252-A1 SIGMA RECEPTOR LIGANDS UCB PHARMA, SA (BE) 2006-03-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080153917-A1 Sigma Receptor Ligands SIGMAR1, TMEM97, OPRL1 EPHX2 2078/4885NPC1 713/4885RAB9A 4371/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.