Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ENPEP | Q07075 | 4/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4866546 | 1.00 | ACE (0.48) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL2230393 | 0.83 | MAPT (0.52) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL29649175 | 0.83 | MAPT (0.52) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL2230396 | 0.83 | MAPT (0.52) | ACEKDM4EMAPTTHRBALOX15 | |
| Hydrochloric Acid SCHEMBL1926275 | 0.82 | MAPT (0.50) | ACEKDM4EMAPTTHRBALOX15 | |
| Hydrochloric Acid SCHEMBL1926272 | 0.82 | MAPT (0.50) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL28653676 | 0.81 | KDM4E (0.46) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL7854879 | 0.80 | GABRP (0.39) | ENPEP | |
| SCHEMBL1396855 | 0.79 | KDM4E (0.50) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL1396852 | 0.79 | KDM4E (0.50) | ACEKDM4EMAPTTHRBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7402407-B1 | Chemically targeted positional identification of post-translationally phosphorylated peptides | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2008-07-22 | — | — | US | disclosed |