SCHEMBL4866620

SCHEMBL4866620

O=C(O)C=CC(=O)Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL688566 0.84
SCHEMBL809089 0.84
SCHEMBL809080 0.84
Fumaric Acid SCHEMBL615 0.80
Maleic Acid SCHEMBL20487516 0.80 TSHR (1.00)
Maleic Acid SCHEMBL2046430 0.80 TSHR (1.00)
Fumaric Acid SCHEMBL3998225 0.80
Maleic Acid SCHEMBL613 0.80
Fumaric Acid SCHEMBL2046433 0.80 TSHR (1.00)
Fumaric Acid SCHEMBL6875 0.80 TSHR (1.00)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1844022-B1 QUINAZOLINE DERIVATIVES FOR INHIBITING CANCER CELL GROWTH AND METHOD FOR THE PREPARATION THEREOF HANMI SCIENCE CO LTD (KR) 2013-08-14 EP claimed
JP-2008525522-A 2008-07-17 JP claimed
US-20080009509-A1 Quinazoline Derivatives For Inhibiting Cancer Cell Growth And Method For The Preparation Thereof HANMI PHARM CO., LTD (KR) 2008-01-10 US claimed
EP-1844022-A1 QUINAZOLINE DERIVATIVES FOR INHIBITING CANCER CELL GROWTH AND METHOD FOR THE PREPARATION THEREOF Hanmi Pharm. Co., Ltd. (KR) 2007-10-17 EP claimed
WO-2006071017-A1 QUINAZOLINE DERIVATIVES FOR INHIBITING CANCER CELL GROWTH AND METHOD FOR THE PREPARATION THEREOF HANMI PHARM. CO., LTD. (KR) 2006-07-06 WO claimed
CN-106957505-B A kind of environment-friendly high fire-retardant electric power, transport cable protection sleeve pipe 深圳市瑞兴利实业有限公司 2019-02-15 CN disclosed
CN-107383627-A A kind of TPV applied to air conditioning for automobiles pipe fitting 安徽雄亚塑胶科技有限公司 2017-11-24 CN disclosed
CN-107207497-A Bicyclic compounds as pest control agents 拜耳作物科学股份公司 2017-09-26 CN disclosed
CN-106957505-A A kind of environment-friendly high fire-retardant electric power, transport cable protection sleeve pipe 段小宁 2017-07-18 CN disclosed
CN-106883548-A A kind of preparation technology of high intensity, high flame retardant cable protecting sleeve 段小宁 2017-06-23 CN disclosed
EP-1844022-B1 QUINAZOLINE DERIVATIVES FOR INHIBITING CANCER CELL GROWTH AND METHOD FOR THE PREPARATION THEREOF HANMI SCIENCE CO LTD (KR) 2013-08-14 EP disclosed
CN-101822948-A Drying substances, preparation and use thereof ORIDION MEDICAL 1987 LTD 2010-09-08 CN disclosed
CN-101822950-A Drying substances, preparation and use thereof ORIDION MEDICAL 1987 LTD 2010-09-08 CN disclosed
US-20080009509-A1 Quinazoline Derivatives For Inhibiting Cancer Cell Growth And Method For The Preparation Thereof HANMI PHARM CO., LTD (KR) 2008-01-10 US disclosed
EP-1844022-A1 QUINAZOLINE DERIVATIVES FOR INHIBITING CANCER CELL GROWTH AND METHOD FOR THE PREPARATION THEREOF Hanmi Pharm. Co., Ltd. (KR) 2007-10-17 EP disclosed
WO-2006071017-A1 QUINAZOLINE DERIVATIVES FOR INHIBITING CANCER CELL GROWTH AND METHOD FOR THE PREPARATION THEREOF HANMI PHARM. CO., LTD. (KR) 2006-07-06 WO disclosed