Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 6/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301511 | 0.85 | POLB (0.64) | ALDH1A1EPHX2TDP1POLBRAB9A | |
| SCHEMBL14694017 | 0.84 | ALDH1A1 (0.66) | ALDH1A1EPHX2TDP1POLBHSD17B10 | |
| SCHEMBL18415483 | 0.84 | POLB (0.77) | ALDH1A1EPHX2TDP1POLBRAB9A | |
| SCHEMBL24575916 | 0.84 | EPHX2 (0.83) | ALDH1A1EPHX2TDP1POLBRAB9A | |
| SCHEMBL1694937 | 0.82 | ALDH1A1 (0.64) | ALDH1A1EPHX2TDP1POLBHSD17B10 | |
| SCHEMBL29410065 | 0.82 | ALDH1A1 (0.74) | ALDH1A1EPHX2TDP1POLBHSD17B10 | |
| SCHEMBL1455280 | 0.82 | ALDH1A1 (0.64) | ALDH1A1EPHX2TDP1POLBHSD17B10 | |
| SCHEMBL553427 | 0.82 | POLB (0.61) | ALDH1A1EPHX2TDP1POLBRAB9A | |
| SCHEMBL19281517 | 0.82 | GAA (0.71) | ALDH1A1POLBKDM4EMAPTMEN1 | |
| SCHEMBL18769149 | 0.81 | HSD17B10 (0.67) | ALDH1A1EPHX2TDP1POLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107567445-A | It can be used as 2 phenyl 3H imidazos [4,5 B] pyridine derivates of mammal EGFR-TK ROR1 activities inhibitor | 坎塞拉有限公司 | 2018-01-09 | — | — | CN | claimed |
| CN-107531615-A | Indenyl compound, pharmaceutical composition and medical application thereof | ADT制药有限责任公司 | 2018-01-02 | — | — | CN | claimed |
| WO-2016124553-A1 | 2-PHENYL-3H-IMIDAZO[4,5-B]PYRIDINE DERIVATES USEFUL AS INHIBITORS OF MAMMALIAN TYROSINE KINASE ROR1 ACTIVITY | KANCERA AB (SE) | 2016-08-11 | — | — | WO | claimed |
| CN-103827080-A | Novel compounds as HIF-1alphainhibitors and manufacturing process thereof | UNIV DONGGUK IND ACAD COOP | 2014-05-28 | — | — | CN | claimed |
| CN-103517991-A | Capture of target DNA and RNA by probes comprising intercalator molecules | QUANTIBACT AS | 2014-01-15 | — | — | CN | claimed |
| US-8148537-B2 | Substituted acetophenones useful as PDE4 inhibitors | LEO PHARMA A/S (DK) | 2012-04-03 | — | — | US | claimed |
| EP-2125736-B1 | SUBSTITUTED ACETOPHENONES USEFUL AS PDE4 INHIBITORS | LEO PHARMA AS (DK) | 2011-03-30 | — | — | EP | claimed |
| US-20100035908-A1 | SUBSTITUTED ACETOPHENONES USEFUL AS PDE4 INHIBITORS | LEO PHARMA (DK) | 2010-02-11 | — | — | US | claimed |
| CN-101611005-A | Be used as the acetophenones of the replacement of PDE4 inhibitor | LEO PHARMA AS (DK) | 2009-12-23 | — | — | CN | claimed |
| EP-2125736-A1 | SUBSTITUTED ACETOPHENONES USEFUL AS PDE4 INHIBITORS | Leo Pharma A/S (DK) | 2009-12-02 | — | — | EP | claimed |
| WO-2008077404-A1 | SUBSTITUTED ACETOPHENONES USEFUL AS PDE4 INHIBITORS | LEO PHARMA A/S (DK) | 2008-07-03 | — | — | WO | claimed |
| EP-1187613-A4 | AMIDE SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES CO (US) | 2002-07-24 | — | — | EP | claimed |
| EP-1187613-A1 | AMIDE SUBSTITUTED IMIDAZOQUINOLINES | 3M Innovative Properties Company (US) | 2002-03-20 | — | — | EP | claimed |
| WO-2000076505-A1 | AMIDE SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2000-12-21 | — | — | WO | claimed |
| CN-1107473-A | 4-Arylamino-benzopyran and related compounds | BRISTOL MYERS SQUIBB CO (US) | 1995-08-30 | — | — | CN | claimed |
| JP-2076841-A | — | — | None | — | — | JP | disclosed |
| EP-3356345-B1 | HETEROARYL DERIVATIVES AS SEPIAPTERIN REDUCTASE INHIBITORS | MAX PLANCK GESELLSCHAFT (DE) | 2023-11-08 | — | — | EP | disclosed |
| CN-1107473-A | 4-Arylamino-benzopyran and related compounds | BRISTOL MYERS SQUIBB CO (US) | 1995-08-30 | — | — | CN | disclosed |
| JP-H0276841-A | PRODUCTION OF AMINOLEVULINIC ACIDS | OSAKA ORGANIC CHEM IND LTD | 1990-03-16 | — | — | JP | disclosed |
| US-4563477-A | Process for the preparation of alpha-(N-pyrrolyl)-derivative acids, the salts and esters thereof; alpha-(N-pyrrolyl)-phenylacetic acids, the esters thereof, pharmaceutical compositions containing them and therapeutical applications thereof | ANTIBIOTICOS, S.A. (ES) | 1986-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035908-A1 | SUBSTITUTED ACETOPHENONES USEFUL AS PDE4 INHIBITORS | PDE4A, PDE4B, PDE3B | ALDH1A1 457/4885EPHX2 871/4885TDP1 433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.