Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL486706 | 0.98 | PLG (0.45) | PLGPOLBHTR2AHTR2C | |
| SCHEMBL27421597 | 0.83 | PLG (0.42) | PLGCYP3A4 | |
| SCHEMBL3068478 | 0.83 | POLB (0.53) | PLGPOLB | |
| Succinic Acid SCHEMBL9425597 | 0.76 | POLB (0.45) | PLGPOLB | |
| Succinic Acid SCHEMBL9425281 | 0.76 | POLB (0.45) | PLGPOLB | |
| Succinic Acid SCHEMBL9425252 | 0.76 | POLB (0.45) | PLGPOLB | |
| Succinic Acid SCHEMBL9426818 | 0.75 | POLB (0.44) | PLGPOLB | |
| SCHEMBL4768930 | 0.74 | CYP3A4 (0.40) | PLGCYP3A4 | |
| SCHEMBL7366091 | 0.74 | POLB (0.58) | PLGPOLBCYP3A4 | |
| SCHEMBL4054752 | 0.73 | GLB1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812391-A2 | PROCESS OF MAKING FENTANYL INTERMEDIATES | Boehringer Ingelheim Chemicals, Inc. (US) | 2007-08-01 | — | — | EP | claimed |
| WO-2006055321-A2 | PROCESS OF MAKING FENTANYL INTERMEDIATES | BOEHRINGER INGELHEIM CHEMICALS, INC. (US) | 2006-05-26 | — | — | WO | claimed |
| CN-104254527-B | The quinoline of antibacterial | 詹森药业有限公司 | 2017-05-31 | — | — | CN | disclosed |
| EP-2410854-B1 | SUBSTITUTED 1, 4-DIOXA-8-AZASPIRO Ý4,5¨DECANES USEFUL AS FUNGICIDES AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2016-06-29 | — | — | EP | disclosed |
| US-8841296-B2 | Substituted 1, 4-dioxa-8-azaspiro[4,5]decanes useful as fungicides and a process for the preparation thereof | Council of Scientific and Industrial Research, Anusandhan Bhawan, Rafi Marg (IN) | 2014-09-23 | — | — | US | disclosed |
| US-20120225877-A1 | SUBSTITUTED 1, 4-DIOXA-8-AZASPIRO[4,5]DECANES USEFUL AS FUNGICIDES AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH; ANUSANDHAN BHAWAN, RAFI MARG. (IN) | 2012-09-06 | — | — | US | disclosed |
| EP-2410854-A2 | SUBSTITUTED 1, 4-DIOXA-8-AZASPIRO Ý4,5¨DECANES USEFUL AS FUNGICIDES AND A PROCESS FOR THE PREPARATION THEREOF | Council of Scientific & Industrial Research (IN) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010109299-A2 | SUBSTITUTED 1, 4-DIOXA-8-AZASPIRO [4,5] DECANES USEFUL AS FUNGICIDES AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2010-09-30 | — | — | WO | disclosed |
| CN-100415716-C | 1-(1,2-disubstituted piperidyl)-4-substituted diethylenediamine derivative | JANSSEN PHARMACENTIC N V (BE) | 2008-09-03 | — | — | CN | disclosed |
| EP-1812391-A2 | PROCESS OF MAKING FENTANYL INTERMEDIATES | Boehringer Ingelheim Chemicals, Inc. (US) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006055321-A2 | PROCESS OF MAKING FENTANYL INTERMEDIATES | BOEHRINGER INGELHEIM CHEMICALS, INC. (US) | 2006-05-26 | — | — | WO | disclosed |
| CN-1438220-A | 1-(1,2-disubstituted piperidyl)-4-substituted diethylenediamine derivative | JANSSEN PHARMACENTIC N V (BE) | 2003-08-27 | — | — | CN | disclosed |
| CN-1117744-C | 1- (1, 2-disubstituted piperidinyl) -4-substituted piperazine derivatives | JANSSEN PHARMACEUTICA NV (BE) | 2003-08-13 | — | — | CN | disclosed |
| CN-1205699-A | 1- (1, 2-disubstituted piperidinyl) -4-substituted piperazine derivatives | JANSSEN PHARMACEUTICA NV (BE) | 1999-01-20 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120225877-A1 | SUBSTITUTED 1, 4-DIOXA-8-AZASPIRO[4,5]DECANES USEFUL AS FUNGICIDES AND A PROCESS FOR THE PREPARATION THEREOF | CYP4X1, CYP51A1, CYP1A1 | PLG 4769/4885POLB 4408/4885CYP3A4 20/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.