Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 17/20 | 0.50 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4878182 | 0.89 | TLR7 (0.38) | TLR7TLR8ARHRH4 | |
| SCHEMBL4879922 | 0.86 | TLR8 (0.44) | TLR7TLR8AR | |
| SCHEMBL4870128 | 0.86 | TLR7 (0.39) | TLR7TLR8ARHRH4 | |
| SCHEMBL4793175 | 0.85 | TLR7 (0.50) | TLR7TLR8 | |
| SCHEMBL4881714 | 0.84 | TLR7 (0.40) | TLR7TLR8 | |
| SCHEMBL4794615 | 0.82 | TLR7 (0.52) | TLR7TLR8 | |
| SCHEMBL4793503 | 0.81 | TLR7 (0.47) | TLR7TLR8 | |
| SCHEMBL4870279 | 0.81 | TLR7 (0.48) | TLR7TLR8 | |
| SCHEMBL4876728 | 0.81 | TLR7 (0.40) | TLR7TLR8 | |
| SCHEMBL4873466 | 0.81 | TLR7 (0.45) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513524-A4 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES CO (US) | 2008-09-03 | — | — | EP | disclosed |
| EP-1513524-A2 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M Innovative Properties Company (US) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003103584-A2 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-12-18 | — | — | WO | disclosed |