Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | SGK1 | O00141 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4878182 | 0.97 | TLR7 (0.38) | TLR7TLR8SGK1ARFAAH | |
| SCHEMBL4867490 | 0.86 | TLR7 (0.50) | TLR7TLR8ARHRH4 | |
| SCHEMBL4881712 | 0.84 | TLR7 (0.34) | TLR7AR | |
| SCHEMBL4879922 | 0.84 | TLR8 (0.44) | TLR7TLR8AR | |
| SCHEMBL4881714 | 0.84 | TLR7 (0.40) | TLR7TLR8 | |
| SCHEMBL4792665 | 0.84 | TLR7 (0.40) | TLR7TLR8CYP3A4TSHR | |
| SCHEMBL4793073 | 0.83 | TLR7 (0.39) | TLR7TLR8FAAHCYP3A4 | |
| SCHEMBL4870184 | 0.81 | TLR7 (0.35) | TLR7SGK1ARCYP3A4MAPK1 | |
| SCHEMBL4791595 | 0.81 | CSNK2A1 (0.37) | TLR7 | |
| SCHEMBL6721688 | 0.81 | CSNK2A1 (0.37) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513524-A4 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES CO (US) | 2008-09-03 | — | — | EP | disclosed |
| EP-1513524-A2 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M Innovative Properties Company (US) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003103584-A2 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-12-18 | — | — | WO | disclosed |