Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 2/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | AGXT | P21549 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1822033 | 0.93 | MAOB (0.47) | TAAR1MAOBMAOAIDO1AGXT | |
| Hydrochloric Acid SCHEMBL3966019 | 0.92 | IDO1 (0.47) | TAAR1MAOBMAOAIDO1AGXT | |
| SCHEMBL1824988 | 0.92 | SLC6A4 (0.46) | TAAR1MAOBMAOAIDO1AGXT | |
| Hydrochloric Acid SCHEMBL3967323 | 0.90 | IDO1 (0.46) | TAAR1MAOBMAOAIDO1AGXT | |
| SCHEMBL1824702 | 0.86 | MAOB (0.55) | ALDH1A1CYP3A4TAAR1MAOBMAOA | |
| SCHEMBL1820867 | 0.86 | MAOB (0.54) | TDP1ALDH1A1CYP3A4MAOBMAOA | |
| Hydrochloric Acid SCHEMBL30293103 | 0.84 | MAOB (0.53) | TDP1ALDH1A1CYP3A4TAAR1MAOB | |
| Hydrochloric Acid SCHEMBL3966839 | 0.84 | MAOB (0.52) | TDP1MAPK1ALDH1A1CYP3A4MAOB | |
| SCHEMBL28637021 | 0.84 | MAOB (0.52) | TDP1ALDH1A1CYP3A4MAOBMAOA | |
| SCHEMBL4868057 | 0.84 | SLC6A4 (0.40) | TDP1MAPK1ALDH1A1CYP3A4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7423035-B2 | Substituted cycloalkyl derivatives, process for the manufacture thereof and use thereof as medicament | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-09-09 | — | — | US | disclosed |
| US-20050261286-A1 | Substituted cycloalkyl derivatives, process for the manufacture thereof and use thereof as medicament | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261286-A1 | Substituted cycloalkyl derivatives, process for the manufacture thereof and use thereof as medicament | CHRM1, CHRM2, CHRM3 | TDP1 3789/4885MAPK1 3429/4885ALDH1A1 1051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.