Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 5/20 | 0.57 |
| ▸ | HTR7 | P34969 | 3/20 | 0.54 |
| ▸ | HTR1A | P08908 | 3/20 | 0.54 |
| ▸ | HTR2A | P28223 | 2/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | HTR6 | P50406 | 4/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.47 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.47 |
| ▸ | MCOLN1 | Q9GZU1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4879267 | 0.87 | SOAT1 (0.62) | SOAT1 | |
| SCHEMBL5469501 | 0.86 | SOAT1 (0.53) | SOAT1HTR7HTR1AHTR2ASLC6A4 | |
| SCHEMBL4876911 | 0.85 | SOAT1 (0.52) | SOAT1HTR7HTR1AHTR2ASLC6A4 | |
| SCHEMBL4883881 | 0.83 | OPRM1 (0.53) | SOAT1ALDH1A1 | |
| SCHEMBL4872157 | 0.81 | KMT2A (0.51) | SOAT1HTR7HTR1AHTR2ASLC6A4 | |
| SCHEMBL5470497 | 0.81 | SOAT1 (0.73) | SOAT1 | |
| SCHEMBL14520330 | 0.80 | SOAT1 (0.62) | SOAT1HTR1A | |
| SCHEMBL14520326 | 0.80 | SOAT1 (0.62) | SOAT1HTR1A | |
| SCHEMBL5475890 | 0.79 | SOAT1 (0.70) | SOAT1 | |
| SCHEMBL14520354 | 0.79 | SOAT1 (0.69) | SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080096922-A1 | Novel Sulfonamide derivative | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2008-04-24 | — | — | US | disclosed |
| EP-1736467-A1 | NOVEL SULFONAMIDE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2006-12-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096922-A1 | Novel Sulfonamide derivative | NR4A1, NR4A2, NR4A3 | SOAT1 502/4885HTR7 1840/4885HTR1A 2072/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.