Sugi Predict

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Hydrochloric Acid

Hydrochloric Acid

SCHEMBL4869125

Cc1c(/N=N/c2sc(Br)c[n+]2C)c2ccccc2n1C.[Cl-]

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ACHE known ✓ P22303 2/20 0.33
▸ CHRM1 known ✓ P11229 1/20 0.32
▸ KMT2A Q03164 2/20 0.37
▸ TSHR P16473 1/20 0.37
▸ ALDH1A1 P00352 5/20 0.34
▸ MAPT P10636 3/20 0.34
▸ TDP1 Q9NUW8 2/20 0.34
▸ GAA P10253 2/20 0.33
▸ HPGD P15428 2/20 0.33
▸ KDM4E B2RXH2 2/20 0.33
▸ CA12 O43570 1/20 0.33
▸ CA1 P00915 1/20 0.33
▸ CA2 P00918 1/20 0.33
▸ CA9 Q16790 1/20 0.33
▸ GLA P06280 1/20 0.33
▸ CYP2C19 P33261 1/20 0.33
▸ HTT P42858 1/20 0.33
▸ HSD17B10 Q99714 1/20 0.33
▸ NPSR1 Q6W5P4 2/20 0.33
▸ BCHE P06276 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4869128 1.00 KMT2A (0.37) KMT2ATSHRALDH1A1MAPTTDP1
SCHEMBL4874732 0.99 KMT2A (0.38) KMT2ATSHRALDH1A1MAPTTDP1
SCHEMBL4874728 0.99 KMT2A (0.38) KMT2ATSHRALDH1A1MAPTTDP1
Bromide SCHEMBL4868935 0.98 KMT2A (0.37) KMT2ATSHRALDH1A1MAPTTDP1
Bromide SCHEMBL4868931 0.98 KMT2A (0.37) KMT2ATSHRALDH1A1MAPTTDP1
SCHEMBL4872461 0.89 CA12 (0.38) KMT2ATSHRALDH1A1MAPTTDP1
Hydrochloric Acid SCHEMBL4872335 0.88 KMT2A (0.39) KMT2ATSHRALDH1A1MAPTTDP1
Hydrochloric Acid SCHEMBL4872332 0.88 KMT2A (0.39) KMT2ATSHRALDH1A1MAPTTDP1
SCHEMBL4870015 0.86 KMT2A (0.39) KMT2ATSHRALDH1A1MAPTTDP1
SCHEMBL4870021 0.86 KMT2A (0.39) KMT2ATSHRALDH1A1MAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1730239-B1 LIGHTENING COLORANT CONTAINING INDOLYL THIAZOLIUM AZO DYES WELLA AG (DE) 2007-05-02 — — EP claimed
US-7431741-B2 Brightening colorant with indolythiazolium dyes WELLA AG (DE) 2008-10-07 — — US disclosed
US-20070180631-A1 Brightening colorant with indolythiazolium dyes Wella GmbH (DE) 2007-08-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070180631-A1 Brightening colorant with indolythiazolium dyes KRT18, TUBB1, IK ACHE 1336/4885CHRM1 2706/4885KMT2A 1177/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.