SCHEMBL4869416

SCHEMBL4869416

F[C](F)C(Cl)C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16241793 0.71
SCHEMBL9812050 0.67
SCHEMBL20679236 0.67 ALDH1A1 (0.35)
SCHEMBL4822731 0.67
SCHEMBL2943317 0.67
SCHEMBL4824001 0.67
SCHEMBL2950232 0.67
SCHEMBL15993837 0.65
SCHEMBL1316837 0.65
SCHEMBL45610 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8418530-B1 Compositions and methods for detecting leaks in HVAC/R systems MAINSTREAM ENGINEERING CORPORATION (US) 2013-04-16 US disclosed
US-7429557-B2 Replacement solvents having improved properties and methods of using the same MAINSTREAM ENGINEERING CORPORATION (US) 2008-09-30 US disclosed
EP-1623015-A4 DNA VACCINE EXPRESSING HA1 OF EQUINE-2 INFLUENZA VIRUS UNIV OKLAHOMA STATE (US) 2007-10-10 EP disclosed
US-20060166851-A1 Replacement solvents having improved properties and methods of using the same MAINSTREAM ENGINEERING CORP. 2006-07-27 US disclosed
EP-1623015-A2 DNA VACCINE EXPRESSING HA1 OF EQUINE-2 INFLUENZA VIRUS THE BOARD OF REGENTS FOR OKLAHOMA STATE UNIVERSITY (US) 2006-02-08 EP disclosed
WO-2005014778-A2 DNA VACCINE EXPRESSING HA1 OF EQUINE-2 INFLUENZA VIRUS THE BOARD OF REGENTS FOR OKLAHOMA STATE UNIVERSITY (US) 2005-02-17 WO disclosed
EP-0583719-A1 Compositions comprising the 1-chloro-2,2,2-trifluoroethyl difluoromethyl ehter and partially fluorinated alcanols Solvay Fluor und Derivate GmbH (DE) 1994-02-23 EP disclosed