Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGMT | P16455 | 6/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | MPO | P05164 | 1/20 | 0.49 |
| ▸ | TPO | P07202 | 1/20 | 0.49 |
| ▸ | EPX | P11678 | 1/20 | 0.49 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.47 |
| ▸ | CDK1 | P06493 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 3/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.45 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5930450 | 0.88 | MGMT (0.58) | MGMTCYP3A4MPOTPOEPX | |
| SCHEMBL11255779 | 0.86 | MGMT (0.56) | MGMTCYP3A4MPOTPOEPX | |
| SCHEMBL25500746 | 0.85 | MGMT (0.55) | MGMTCYP3A4MPOTPOEPX | |
| SCHEMBL2153643 | 0.84 | MGMT (0.54) | MGMTCYP3A4MPOTPOEPX | |
| SCHEMBL8898522 | 0.83 | MGMT (0.53) | MGMTCYP3A4MPOTPOEPX | |
| SCHEMBL3209666 | 0.82 | CDK1 (0.60) | MGMTCYP3A4MPOTPOEPX | |
| SCHEMBL8896045 | 0.82 | MGMT (0.52) | MGMTCYP3A4MPOTPOEPX | |
| SCHEMBL2734851 | 0.82 | MGMT (0.56) | MGMTCYP3A4MPOTPOEPX | |
| SCHEMBL14963617 | 0.81 | MGMT (0.51) | MGMTCYP3A4MPOTPOEPX | |
| SCHEMBL8898448 | 0.81 | MGMT (0.51) | MGMTCYP3A4MPOTPOEPX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050080098-A1 | Crystal and solvate of 2-amino-6-benzyloxypurine and production methods thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-04-14 | — | — | US | claimed |
| EP-1492791-A1 | CRYSTAL AND SOLVATE OF 2-AMINO-6-BENZYLOXYPURINE AND PRODUCTION METHODS THEREOF | Sumitomo Chemical Company, Limited (JP) | 2005-01-05 | — | — | EP | claimed |
| WO-2003084957-A1 | CRYSTAL AND SOLVATE OF 2-AMINO-6-BENZYLOXYPURINE AND PRODUCTION METHODS THEREOF | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2003-10-16 | — | — | WO | claimed |
| US-7345170-B2 | Crystal and solvate of 2-amino-6-benzyloxypurine and production methods thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-03-18 | — | — | US | disclosed |
| US-20050080098-A1 | Crystal and solvate of 2-amino-6-benzyloxypurine and production methods thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-04-14 | — | — | US | disclosed |
| EP-1492791-A1 | CRYSTAL AND SOLVATE OF 2-AMINO-6-BENZYLOXYPURINE AND PRODUCTION METHODS THEREOF | Sumitomo Chemical Company, Limited (JP) | 2005-01-05 | — | — | EP | disclosed |
| WO-2003084957-A1 | CRYSTAL AND SOLVATE OF 2-AMINO-6-BENZYLOXYPURINE AND PRODUCTION METHODS THEREOF | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2003-10-16 | — | — | WO | disclosed |