Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 5/20 | 0.60 |
| ▸ | MGMT | P16455 | 6/20 | 0.53 |
| ▸ | MPO | P05164 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | TPO | P07202 | 1/20 | 0.53 |
| ▸ | EPX | P11678 | 1/20 | 0.53 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.49 |
| ▸ | CDK2 | P24941 | 3/20 | 0.49 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.49 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.49 |
| ▸ | ATP4A | P20648 | 2/20 | 0.47 |
| ▸ | ATP4B | P51164 | 2/20 | 0.47 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17450122 | 0.84 | DAPK1 (0.47) | CDK1MGMTMPOCYP3A4TPO | |
| SCHEMBL4869642 | 0.82 | MGMT (0.62) | CDK1MGMTMPOCYP3A4TPO | |
| SCHEMBL26226179 | 0.82 | CDK1 (0.55) | CDK1MGMTMPOCYP3A4TPO | |
| SCHEMBL12959071 | 0.81 | MGMT (0.53) | CDK1MGMTMPOCYP3A4TPO | |
| SCHEMBL26211037 | 0.80 | CDK1 (0.47) | CDK1MGMTMPOCYP3A4TPO | |
| SCHEMBL12522765 | 0.80 | CDK1 (0.50) | CDK1CCNB1CDK2CYP2C19CCNE1 | |
| SCHEMBL8896045 | 0.79 | MGMT (0.52) | CDK1MGMTMPOCYP3A4TPO | |
| SCHEMBL2153643 | 0.79 | MGMT (0.54) | CDK1MGMTMPOCYP3A4TPO | |
| SCHEMBL8008235 | 0.78 | CDK1 (0.62) | CDK1MPOCYP3A4CCNB1CDK2 | |
| SCHEMBL8898522 | 0.78 | MGMT (0.53) | CDK1MGMTMPOCYP3A4TPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8211899-B2 | Artificial nucleic acid bases and their use in base pairing natural nucleic acid bases | INTER-UNIVERSITY RESEARCH INSTITUTE CORPORATION NATIONAL INSTITUTE OF NATURAL SCIENCES (JP) | 2012-07-03 | — | — | US | disclosed |
| US-20100036108-A1 | Universal Base | KATAOKA, MASANORI (JP) | 2010-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100036108-A1 | Universal Base | NSUN2, TRMT1, TARBP1 | CDK1 2669/4885MGMT 678/4885MPO 3589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.