Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 5/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8919552 | 0.88 | KMT2A (0.57) | TEAD1S1PR5KMT2AL3MBTL1JAK1 | |
| SCHEMBL25473933 | 0.86 | TEAD1 (0.49) | TEAD1KMT2AL3MBTL1 | |
| SCHEMBL22719762 | 0.86 | TEAD1 (0.49) | TEAD1KMT2AL3MBTL1 | |
| SCHEMBL25473941 | 0.86 | TEAD1 (0.49) | TEAD1KMT2AL3MBTL1 | |
| SCHEMBL29725714 | 0.81 | CCR2 (0.55) | TEAD1KMT2AL3MBTL1DRD2 | |
| SCHEMBL29725664 | 0.81 | CCR2 (0.55) | TEAD1KMT2AL3MBTL1DRD2 | |
| SCHEMBL4433119 | 0.81 | CCR2 (0.55) | TEAD1KMT2AL3MBTL1DRD2 | |
| SCHEMBL21499091 | 0.81 | HRH3 (0.41) | TEAD1KMT2AL3MBTL1JAK1HRH3 | |
| SCHEMBL29686800 | 0.81 | HRH3 (0.41) | TEAD1KMT2AL3MBTL1JAK1HRH3 | |
| SCHEMBL4848198 | 0.80 | KMT2A (0.60) | GAAKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008010238-A2 | ANTIDIABETIC AZABICYCLO [3. 1. 0] HEXAN COMPOUNDS | LUPIN LIMITED (IN) | 2008-01-24 | — | — | WO | disclosed |
| WO-2008010238-A2 | ANTIDIABETIC AZABICYCLO [3. 1. 0] HEXAN COMPOUNDS | LUPIN LIMITED (IN) | 2008-01-24 | — | — | WO | disclosed |