SCHEMBL4869946

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14003524	0.90	PIK3CD (0.55)	PIK3CDPIK3CAPIK3CBAKT2GSK3B
	SCHEMBL4875291	0.86	PIK3CD (0.58)	PIK3CDPIK3CAPIK3CBAKT2GSK3B
	SCHEMBL4869767	0.84	AKT2 (0.53)	PIK3CDPIK3CAPIK3CBAKT2GSK3B
	SCHEMBL4874896	0.83	AKT2 (0.45)	AKT2GSK3BALDH1A1SLC6A4SLC6A3
	SCHEMBL4865960	0.82	PIK3CD (0.55)	PIK3CDPIK3CAPIK3CBAKT2GSK3B
	SCHEMBL4879519	0.74	PIK3CD (0.56)	PIK3CDPIK3CAPIK3CBAKT2GSK3B
	SCHEMBL30169542	0.72	PIK3CD (0.73)	PIK3CDPIK3CAPIK3CBALDH1A1IP6K1
	SCHEMBL4878824	0.72	PIK3CD (0.73)	PIK3CDPIK3CAPIK3CBALDH1A1IP6K1
	SCHEMBL4873386	0.72	PIK3CD (0.68)	PIK3CDPIK3CAPIK3CBALDH1A1IP6K1
	SCHEMBL4876138	0.71	PIK3CD (0.71)	PIK3CDPIK3CAPIK3CBALDH1A1IP6K1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.