SCHEMBL4874896

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4877211	0.83	AKT2 (0.44)	AKT2GSK3BDCAF15TRPV1TYMS
	SCHEMBL4869946	0.83	PIK3CD (0.55)	AKT2GSK3BDCAF15SLC6A4SLC6A3
	SCHEMBL16298728	0.77	TERT (0.55)	PARP14LMNAGAASMN1; SMN2KDM4E
	SCHEMBL14003524	0.73	PIK3CD (0.55)	AKT2GSK3BKDRALDH1A1
	SCHEMBL4869404	0.72	KMT2A (0.35)	DCAF15SLC6A4PARP14HTR1AHTR7
	SCHEMBL6670119	0.71	TYMS (0.63)	TRPV1TYMSLMNAGAASMN1; SMN2
	SCHEMBL4875291	0.69	PIK3CD (0.58)	AKT2GSK3BALDH1A1
	SCHEMBL4869767	0.67	AKT2 (0.53)	AKT2GSK3BKDRALDH1A1
	SCHEMBL20509747	0.67	KDM4E (0.59)	LMNAGAASMN1; SMN2KDM4ENPC1
	SCHEMBL5166600	0.66	SLC6A4 (0.64)	AKT2GSK3BSLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.