⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1090972 | 0.76 | KDM4E (0.36) | — | |
| SCHEMBL18228429 | 0.67 | CYP1A2 (0.32) | — | |
| SCHEMBL5483645 | 0.66 | ALDH1A1 (0.55) | — | |
| SCHEMBL31115164 | 0.66 | ALDH1A1 (0.55) | — | |
| SCHEMBL6247283 | 0.66 | KDM4E (0.41) | — | |
| SCHEMBL7118514 | 0.65 | ALDH1A1 (0.37) | — | |
| SCHEMBL17512890 | 0.63 | KMT2A (0.50) | — | |
| SCHEMBL30125497 | 0.61 | ALDH1A1 (0.44) | — | |
| SCHEMBL2951873 | 0.61 | ALDH1A1 (0.44) | — | |
| SCHEMBL18806848 | 0.61 | KDM4E (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7449570-B2 | Use of nucleoside compounds for nonsense suppression and the treatment of genetic diseases | PTC THERAPEUTICS, INC. (US) | 2008-11-11 | — | — | US | disclosed |
| US-20060166926-A1 | Use of nucleoside compounds for nonsense suppression and the treatment of genetic diseases | PTC THERAPEUTICS, INC. | 2006-07-27 | — | — | US | disclosed |