Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | APAF1 | O14727 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | TDP2 | O95551 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1948081 | 0.94 | MAPT (0.48) | MAPTSMN1; SMN2NPSR1KMT2AMEN1 | |
| SCHEMBL5489120 | 0.91 | MAPT (0.46) | MAPTSMN1; SMN2NPSR1KMT2AMEN1 | |
| SCHEMBL14571066 | 0.90 | NPSR1 (0.48) | MAPTSMN1; SMN2NPSR1KMT2AMEN1 | |
| SCHEMBL13854618 | 0.90 | NPSR1 (0.48) | MAPTSMN1; SMN2NPSR1KMT2AMEN1 | |
| SCHEMBL8044893 | 0.89 | NPSR1 (0.61) | NPSR1KMT2AMEN1TSHRAPAF1 | |
| SCHEMBL14160277 | 0.88 | NR3C2 (0.54) | MAPTSMN1; SMN2NPSR1KMT2AMEN1 | |
| SCHEMBL14160280 | 0.88 | NR3C2 (0.54) | MAPTSMN1; SMN2NPSR1KMT2AMEN1 | |
| SCHEMBL12037062 | 0.88 | KMT2A (0.56) | KMT2AMEN1TSHRNPC1ALDH1A1 | |
| SCHEMBL14160275 | 0.88 | NR3C2 (0.54) | MAPTSMN1; SMN2NPSR1KMT2AMEN1 | |
| SCHEMBL14160274 | 0.87 | NPC1 (0.50) | MAPTSMN1; SMN2NPSR1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7321066-B2 | Method for producing aromatic diamine derivative | IDEMITSU KOSAN CO., LTD. (JP) | 2008-01-22 | — | — | US | disclosed |
| US-20060063952-A1 | Method for producing aromatic diamine derivative | IDEMITSU KOSAN CO., LTD. (JP) | 2006-03-23 | — | — | US | disclosed |
| EP-1593665-A1 | METHOD FOR PRODUCING AROMATIC DIAMINE DERIVATIVE | IDEMITSU KOSAN CO., LTD. (JP) | 2005-11-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060063952-A1 | Method for producing aromatic diamine derivative | NAT1, AHR, AADAC | MAPT 3095/4885SMN1; SMN2 3554/4885NPSR1 2056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.