Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4849735 | 0.96 | NPSR1 (0.45) | MAPTSMN1; SMN2NPSR1KMT2AMEN1 | |
| SCHEMBL4849374 | 0.91 | NPSR1 (0.50) | NPSR1KMT2AMEN1TSHRAPAF1 | |
| SCHEMBL4870751 | 0.91 | MAPT (0.54) | MAPTSMN1; SMN2NPSR1KMT2AMEN1 | |
| SCHEMBL1948081 | 0.85 | MAPT (0.48) | MAPTSMN1; SMN2NPSR1KMT2AMEN1 | |
| Acetic Acid SCHEMBL30426409 | 0.82 | SMN1; SMN2 (0.58) | MAPTSMN1; SMN2TSHRNPC1ALDH1A1 | |
| SCHEMBL13854618 | 0.81 | NPSR1 (0.48) | MAPTSMN1; SMN2NPSR1KMT2AMEN1 | |
| SCHEMBL14571066 | 0.81 | NPSR1 (0.48) | MAPTSMN1; SMN2NPSR1KMT2AMEN1 | |
| SCHEMBL8044893 | 0.80 | NPSR1 (0.61) | NPSR1KMT2AMEN1TSHRAPAF1 | |
| SCHEMBL12037062 | 0.79 | KMT2A (0.56) | KMT2AMEN1TSHRNPC1ALDH1A1 | |
| SCHEMBL14160277 | 0.79 | NR3C2 (0.54) | MAPTSMN1; SMN2NPSR1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070179318-A1 | Aromatic amine derivative and organic electroluminescence device using same | IDEMITSU KOSAN CO., LTD. (JP) | 2007-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070179318-A1 | Aromatic amine derivative and organic electroluminescence device using same | TYR, KCNN2, MAOA | MAPT 134/4885SMN1; SMN2 1621/4885NPSR1 4578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.