Urea

Urea

SCHEMBL4871038

C=C(C)C(=O)OCC.C=CO.NC(N)=O

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.50
TSHR P16473 4/20 0.44
GLO1 Q04760 1/20 0.44
ALOX15 P16050 1/20 0.43
ALDH1A1 P00352 8/20 0.42
NPSR1 Q6W5P4 1/20 0.39
LMNA P02545 1/20 0.39
HSD17B10 Q99714 1/20 0.39
MGAM O43451 1/20 0.38
GAA P10253 1/20 0.38
SI P14410 1/20 0.38
MGAM2 Q2M2H8 1/20 0.38
TDP1 Q9NUW8 1/20 0.37
MAPT P10636 2/20 0.36
CYP2D6 P10635 2/20 0.36
CYP2C19 P33261 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urea SCHEMBL28331735 0.92 THRB (0.57) THRBTSHRGLO1ALOX15ALDH1A1
SCHEMBL5831741 0.90 THRB (0.55) THRBTSHRGLO1ALOX15ALDH1A1
Urea SCHEMBL1071963 0.90 THRB (0.55) THRBTSHRGLO1ALOX15ALDH1A1
Acrylamide SCHEMBL5476599 0.88 THRB (0.50) THRBTSHRGLO1ALOX15ALDH1A1
Acetamide SCHEMBL28712443 0.87 THRB (0.57) THRBTSHRGLO1ALOX15ALDH1A1
Carbamic Acid SCHEMBL4630918 0.85 THRB (0.55) THRBTSHRGLO1ALOX15ALDH1A1
Propene SCHEMBL20853733 0.85 THRB (0.55) THRBTSHRGLO1ALOX15ALDH1A1
SCHEMBL27798356 0.85 THRB (0.55) THRBTSHRGLO1ALOX15ALDH1A1
Butadiene SCHEMBL2354922 0.85 THRB (0.55) THRBTSHRGLO1ALOX15ALDH1A1
Formic Acid SCHEMBL28329542 0.85 THRB (0.55) THRBTSHRGLO1ALOX15ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1861469-B1 PIGMENT DISPERSANT, METHOD OF MAKING COATING COMPOSITIONS, AND COATING COMPOSITIONS BASF COATINGS GMBH (DE) 2014-05-07 EP disclosed
US-7417102-B2 Pigment dispersant, method of making coating compositions, and coating compositions BASF CORPORATION (US) 2008-08-26 US disclosed
EP-1861469-A1 PIGMENT DISPERSANT, METHOD OF MAKING COATING COMPOSITIONS, AND COATING COMPOSITIONS Basf Corporation (US) 2007-12-05 EP disclosed
US-20070062412-A1 PIGMENT DISPERSANT, METHOD OF MAKING COATING COMPOSITIONS, AND COATING COMPOSITIONS BASF CORPORATION (US) 2007-03-22 US disclosed
US-20060217485-A1 Pigment dispersant, method of making coating compositions, and coating compositions BASF CORPORATION (US) 2006-09-28 US disclosed
WO-2006102341-A1 PIGMENT DISPERSANT, METHOD OF MAKING COATING COMPOSITIONS, AND COATING COMPOSITIONS BASF CORPORATION (US) 2006-09-28 WO disclosed