Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | MB | P02144 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14198044 | 0.82 | KDM4E (0.60) | PTGS2MAPTKDM4ERAB9ANPSR1 | |
| SCHEMBL13843254 | 0.81 | TP53 (0.55) | MAPTKDM4ERAB9ANPSR1SMN1; SMN2 | |
| SCHEMBL8038684 | 0.80 | NAMPT (0.60) | PTGS2MAPTKDM4ERAB9ANPSR1 | |
| SCHEMBL2674745 | 0.79 | TP53 (0.74) | KDM4EL3MBTL1HTTALDH1A1TDP1 | |
| SCHEMBL28396692 | 0.79 | KDM4E (0.57) | PTGS2MAPTKDM4ERAB9ANPSR1 | |
| SCHEMBL5392566 | 0.78 | KDM4E (0.78) | KDM4ERAB9AKMT2AALDH1A1CYP3A4 | |
| SCHEMBL3132131 | 0.78 | KDM4E (0.78) | KDM4ERAB9AKMT2AALDH1A1CYP3A4 | |
| SCHEMBL3132127 | 0.78 | KDM4E (0.78) | KDM4ERAB9AKMT2AALDH1A1CYP3A4 | |
| SCHEMBL10944710 | 0.78 | SMN1; SMN2 (0.64) | MAPTKDM4ERAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL7941711 | 0.78 | SMN1; SMN2 (0.64) | MAPTKDM4ERAB9ASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7326407-B2 | Amine, amide, sulphonamide and carbamate derivatives of benzalmalonic salts and photoprotective cosmetic compositions comprised thereof | L'OREAL (FR) | 2008-02-05 | — | — | US | disclosed |
| US-7326407-B2 | Amine, amide, sulphonamide and carbamate derivatives of benzalmalonic salts and photoprotective cosmetic compositions comprised thereof | L'OREAL (FR) | 2008-02-05 | — | — | US | disclosed |
| US-7326407-B2 | Amine, amide, sulphonamide and carbamate derivatives of benzalmalonic salts and photoprotective cosmetic compositions comprised thereof | L'OREAL (FR) | 2008-02-05 | — | — | US | disclosed |
| US-20060099159-A1 | Novel amine, amide, sulphonamide and carbamate derivatives of benzalmalonic salts and photoprotective cosmetic compositions comprised thereof | L'OREAL (FR) | 2006-05-11 | — | — | US | disclosed |
| US-7008935-B2 | Amine, amide, sulphonamide and carbamate derivatives of benzalmalonic salts and photoprotective cosmetic compositions comprised thereof | L'OREAL (FR) | 2006-03-07 | — | — | US | disclosed |
| US-20040198977-A1 | Novel amine, amide, sulphonamide and carbamate derivatives of benzalmalonic salts and photoprotective cosmetic compositions comprised thereof | SOCIETE L'OREAL S.A. (FR) | 2004-10-07 | — | — | US | disclosed |
| EP-1454896-A1 | Amine, amide, sulfonamide and carbamate derivatives of benzylidenemalonoc acid salts photoprotective cosmetic compositions containing them | L'OREAL (FR) | 2004-09-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060099159-A1 | Novel amine, amide, sulphonamide and carbamate derivatives of benzalmalonic salts and photoprotective cosmetic compositions comprised thereof | ACMSD, KDM6B, AADAC | PTGS2 4209/4885MAPT 615/4885KDM4E 106/4885 |
| US-20040198977-A1 | Novel amine, amide, sulphonamide and carbamate derivatives of benzalmalonic salts and photoprotective cosmetic compositions comprised thereof | ACMSD, KDM6B, AADAC | PTGS2 4209/4885MAPT 615/4885KDM4E 106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.