Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.64 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16291799 | 0.93 | ESR1 (0.65) | ESR1ESR2ALDH1A1MEN1KMT2A | |
| SCHEMBL27443700 | 0.86 | ESR1 (0.78) | ESR1ESR2ALDH1A1MEN1KMT2A | |
| SCHEMBL3035395 | 0.84 | NR3C2 (0.47) | ESR1ESR2ALDH1A1MEN1KMT2A | |
| SCHEMBL9001714 | 0.83 | NR3C2 (0.62) | ESR1ESR2ALDH1A1MEN1KMT2A | |
| SCHEMBL1003807 | 0.83 | NPSR1 (0.61) | ESR1ESR2ALDH1A1MEN1KMT2A | |
| SCHEMBL28584481 | 0.81 | MEN1 (0.54) | ESR1ESR2ALDH1A1MEN1KMT2A | |
| SCHEMBL6555569 | 0.81 | ALDH1A1 (0.51) | ESR1ESR2ALDH1A1MEN1KMT2A | |
| SCHEMBL28324842 | 0.80 | NR3C2 (0.58) | ESR1ESR2ALDH1A1MEN1KMT2A | |
| SCHEMBL9001693 | 0.79 | NPSR1 (0.61) | ESR1ESR2ALDH1A1MEN1KMT2A | |
| SCHEMBL2113010 | 0.78 | ESR1 (0.64) | ESR1ESR2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7321066-B2 | Method for producing aromatic diamine derivative | IDEMITSU KOSAN CO., LTD. (JP) | 2008-01-22 | — | — | US | disclosed |
| CN-100340540-C | Process for producing aromatic diamine derivative | IDEMITSU KOSAN CO (JP) | 2007-10-03 | — | — | CN | disclosed |
| CN-1753860-A | Process for producing aromatic diamine derivative | IDEMITSU KOSAN CO (JP) | 2006-03-29 | — | — | CN | disclosed |
| US-20060063952-A1 | Method for producing aromatic diamine derivative | IDEMITSU KOSAN CO., LTD. (JP) | 2006-03-23 | — | — | US | disclosed |
| EP-1593665-A1 | METHOD FOR PRODUCING AROMATIC DIAMINE DERIVATIVE | IDEMITSU KOSAN CO., LTD. (JP) | 2005-11-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060063952-A1 | Method for producing aromatic diamine derivative | NAT1, AHR, AADAC | ESR1 2813/4885ESR2 661/4885ALDH1A1 188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.