Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 1.00 |
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.81 |
| ▸ | PREP | P48147 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4872095 | 1.00 | SIGMAR1 (1.00) | SIGMAR1HRH3PREP | |
| SCHEMBL452599 | 0.89 | HRH3 (1.00) | SIGMAR1HRH3 | |
| SCHEMBL449941 | 0.89 | HRH3 (1.00) | SIGMAR1HRH3 | |
| SCHEMBL440560 | 0.89 | HRH3 (1.00) | SIGMAR1HRH3 | |
| SCHEMBL15314500 | 0.89 | HRH3 (1.00) | SIGMAR1HRH3 | |
| SCHEMBL440558 | 0.89 | HRH3 (1.00) | SIGMAR1HRH3 | |
| SCHEMBL15314491 | 0.89 | HRH3 (1.00) | SIGMAR1HRH3 | |
| SCHEMBL452598 | 0.89 | HRH3 (1.00) | SIGMAR1HRH3 | |
| SCHEMBL449940 | 0.89 | HRH3 (1.00) | SIGMAR1HRH3 | |
| SCHEMBL452624 | 0.88 | HRH3 (1.00) | SIGMAR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080153917-A1 | Sigma Receptor Ligands | UCB PHARMA, S.A. (BE) | 2008-06-26 | — | — | US | claimed |
| EP-1797036-A1 | SIGMA RECEPTOR LIGANDS | UCB Pharma, S.A. (BE) | 2007-06-20 | — | — | EP | claimed |
| WO-2006027252-A1 | SIGMA RECEPTOR LIGANDS | UCB PHARMA, SA (BE) | 2006-03-16 | — | — | WO | claimed |
| US-20080153917-A1 | Sigma Receptor Ligands | UCB PHARMA, S.A. (BE) | 2008-06-26 | — | — | US | disclosed |
| EP-1797036-A1 | SIGMA RECEPTOR LIGANDS | UCB Pharma, S.A. (BE) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006027252-A1 | SIGMA RECEPTOR LIGANDS | UCB PHARMA, SA (BE) | 2006-03-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080153917-A1 | Sigma Receptor Ligands | SIGMAR1, TMEM97, OPRL1 | SIGMAR1 1/4885HRH3 98/4885PREP 1716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.