Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 2/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | PDE7A | Q13946 | 4/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29398960 | 1.00 | TSHR (1.00) | TSHRMAPK1TDP1VCAM1CA1 | |
| Fluoride SCHEMBL4646971 | 0.98 | TSHR (0.96) | TSHRMAPK1TDP1VCAM1CA1 | |
| SCHEMBL28605170 | 0.92 | TSHR (0.85) | TSHRMAPK1TDP1VCAM1CA1 | |
| Formic Acid SCHEMBL28203199 | 0.90 | TSHR (0.81) | TSHRMAPK1TDP1VCAM1CA1 | |
| Acetonitrile SCHEMBL28603177 | 0.89 | TSHR (0.79) | TSHRMAPK1TDP1VCAM1CA1 | |
| SCHEMBL5804418 | 0.89 | TSHR (0.79) | TSHRMAPK1TDP1VCAM1CA1 | |
| Tetrahydrothiophene SCHEMBL11517766 | 0.86 | MAPK1 (0.73) | TSHRMAPK1TDP1VCAM1CA1 | |
| SCHEMBL27600281 | 0.86 | TSHR (0.73) | TSHRMAPK1TDP1VCAM1CA1 | |
| SCHEMBL9488895 | 0.86 | TSHR (0.73) | TSHRMAPK1TDP1VCAM1LMNA | |
| Phenol SCHEMBL28068488 | 0.86 | MAPK1 (0.73) | TSHRMAPK1TDP1VCAM1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1258 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118239845-A | Method for removing dinitro by-product and purifying 2, 4-dichloronitrobenzene crude product | 云南云天化股份有限公司 | 2024-06-25 | — | — | CN | claimed |
| CN-118179542-A | Carbon-based catalyst, and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-220737508-U | Preparation system of 2, 4-dichloronitrobenzene | 山东金特安全科技有限公司 | 2024-04-09 | — | — | CN | claimed |
| CN-117447328-A | Clean production method of oxyfluorfen | 首建科技有限公司 | 2024-01-26 | — | — | CN | claimed |
| CN-117288860-A | Analysis method of genotoxic impurities in flurbiprofen | 湖南九典宏阳制药有限公司 | 2023-12-26 | — | — | CN | claimed |
| CN-117050524-A | Wear-resistant amphiphobic polyphenylene sulfide composite material and preparation method thereof | 江西聚真科技发展有限公司 | 2023-11-14 | — | — | CN | claimed |
| CN-117003643-A | M-dichlorobenzene continuous nitration process for inhibiting side reaction | 山东科加工业技术研究院有限公司 | 2023-11-07 | — | — | CN | claimed |
| CN-116948202-A | Preparation method of amphiphobic modified polyphenylene sulfide | 江西聚真科技发展有限公司 | 2023-10-27 | — | — | CN | claimed |
| CN-116836063-A | Preparation method of 5-chloro-2-nitroaniline | 浙江普洛康裕制药有限公司 | 2023-10-03 | — | — | CN | claimed |
| CN-113087627-B | Method for synthesizing 2, 4-dichloronitrobenzene by adopting tetraphenyl phosphine iodide as catalyst | 云南云天化股份有限公司 | 2023-08-18 | — | — | CN | claimed |
| WO-1987004148-A1 | CATALYTIC METHOD FOR PRODUCING FLUOROAROMATIC COMPOUNDS USING BRANCHED ALKYL PYRIDINIUM SALTS | MALLINCKRODT, INC. (US) | 1987-07-16 | — | — | WO | claimed |
| EP-0170412-A1 | Benzoselenino[4,3,2-cd]indazole compounds, compositions comprising the compounds and processes for producing the compounds | WARNER-LAMBERT COMPANY (US) | 1986-02-05 | — | — | EP | claimed |
| EP-0043675-B1 | MODIFIED HEMOGLOBINS SUITABLE FOR USE AS OXYGEN CARRIERS FOR BLOOD SUBSTITUTES | AJINOMOTO CO., INC. (JP) | 1984-10-03 | — | — | EP | claimed |
| US-4421694-A | Process for the preparation of nitroanilines | BAYER AKTIENGESELLSCHAFT (DE) | 1983-12-20 | — | — | US | claimed |
| US-4377512-A | ESTERIFICATION INULIN AND REACTING WITH HEMOGLOBIN | AJINOMOTO CO., INC. (JP) | 1983-03-22 | — | — | US | claimed |
| EP-0043675-A1 | Modified hemoglobins suitable for use as oxygen carriers for blood substitutes | AJINOMOTO CO., INC. (JP) | 1982-01-13 | — | — | EP | claimed |
| US-4310711-A | Process for preparing 5-chloro-2-nitrophenol | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-01-12 | — | — | US | claimed |
| US-4230637-A | Process for the preparation of chlorine-substituted aromatic amines | BAYER AKTIENGESELLSCHAFT (DE) | 1980-10-28 | — | — | US | claimed |
| EP-0000805-A1 | Catalytic hydrogenation process for the manufacture of chlorinated aromatic amines | The Clayton Aniline Company Limited (GB) | 1979-02-21 | — | — | EP | claimed |
| US-4124768-A | Process for preparing pure substituted 2,5-diarylamino-terephthalates and the corresponding free acids | HOECHST AKTIENGESELLSCHAFT | 1978-11-07 | — | — | US | claimed |