Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.73 |
| ▸ | TSHR | P16473 | 1/20 | 0.73 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.49 |
| ▸ | PDE7B | Q9NP56 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL28068489 | 0.87 | VCAM1 (0.56) | MAPK1TSHRPDE7APDE7BL3MBTL1 | |
| SCHEMBL487215 | 0.86 | TSHR (1.00) | MAPK1TSHRPDE7APDE7BL3MBTL1 | |
| SCHEMBL29398960 | 0.86 | TSHR (1.00) | MAPK1TSHRPDE7APDE7BL3MBTL1 | |
| Fluoride SCHEMBL4646971 | 0.84 | TSHR (0.96) | MAPK1TSHRPDE7APDE7BL3MBTL1 | |
| Phenol SCHEMBL27752800 | 0.82 | HPGD (0.51) | MAPK1TSHRL3MBTL1CYP3A4ALDH1A1 | |
| SCHEMBL28605170 | 0.82 | TSHR (0.85) | MAPK1TSHRPDE7APDE7BL3MBTL1 | |
| Formic Acid SCHEMBL28203199 | 0.81 | TSHR (0.81) | MAPK1TSHRPDE7ACYP3A4ALDH1A1 | |
| SCHEMBL1551981 | 0.78 | TSHR (0.64) | MAPK1TSHRPDE7ACYP3A4ALDH1A1 | |
| SCHEMBL30923019 | 0.78 | TSHR (0.64) | MAPK1TSHRPDE7ACYP3A4ALDH1A1 | |
| SCHEMBL5804418 | 0.76 | TSHR (0.79) | MAPK1TSHRPDE7APDE7BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105621587-B | A kind of method using potentiometric titrations degradating chloro nitro-aromatic | 浙江大学 | 2018-01-23 | — | — | CN | claimed |
| CN-105621587-A | Method for degrading chloro-nitroaromatic by using sulfate radicals | UNIV ZHEJIANG | 2016-06-01 | — | — | CN | claimed |
| CN-105621587-B | A kind of method using potentiometric titrations degradating chloro nitro-aromatic | 浙江大学 | 2018-01-23 | — | — | CN | disclosed |
| CN-105793252-A | Inhibitors of bruton's tyrosine kinase | 豪夫迈·罗氏有限公司 | 2016-07-20 | — | — | CN | disclosed |
| CN-105621587-A | Method for degrading chloro-nitroaromatic by using sulfate radicals | UNIV ZHEJIANG | 2016-06-01 | — | — | CN | disclosed |