⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4866392 | 0.80 | POLB (0.36) | — | |
| SCHEMBL4870902 | 0.80 | — | — | |
| SCHEMBL4868158 | 0.76 | ALDH1A1 (0.33) | — | |
| SCHEMBL4864629 | 0.73 | GAA (0.41) | — | |
| SCHEMBL4862605 | 0.73 | ABL1 (0.42) | — | |
| SCHEMBL4870722 | 0.72 | NPC1 (0.30) | — | |
| SCHEMBL4867247 | 0.72 | SYK (0.38) | — | |
| SCHEMBL4862478 | 0.71 | SRC (0.33) | — | |
| SCHEMBL4862729 | 0.71 | MAPT (0.32) | — | |
| SCHEMBL4872759 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7332485-B2 | Peptide deformylase inhibitors | SMITHKLINE BEECHAM CORP (US) | 2008-02-19 | — | — | US | disclosed |
| US-20060160802-A1 | Peptide deformylase inhibitors | GLAXO GROUP LIMITED | 2006-07-20 | — | — | US | disclosed |