Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.46 |
| ▸ | TGM2 | P21980 | 2/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.34 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5850749 | 0.83 | THRB (0.46) | THRBTGM2AKT1MAOBALDH1A1 | |
| SCHEMBL10795074 | 0.80 | LIG1 (0.38) | THRBAKT1ALDH1A1MEN1KMT2A | |
| SCHEMBL28450603 | 0.79 | THRB (0.46) | THRBTGM2AKT1MAOBALDH1A1 | |
| SCHEMBL9273225 | 0.78 | THRB (0.43) | THRBTGM2ALDH1A1TSHRTEAD1 | |
| SCHEMBL6927418 | 0.78 | THRB (0.45) | THRBTGM2AKT1MAOBALDH1A1 | |
| SCHEMBL28562182 | 0.78 | THRB (0.45) | THRBTGM2AKT1MAOBALDH1A1 | |
| SCHEMBL30881614 | 0.77 | THRB (0.44) | THRBTGM2AKT1MAOBALDH1A1 | |
| SCHEMBL3006726 | 0.76 | THRB (0.43) | THRBTGM2AKT1ALDH1A1TSHR | |
| SCHEMBL10479978 | 0.75 | THRB (0.56) | THRBTGM2AKT1MAOBALDH1A1 | |
| SCHEMBL351499 | 0.75 | THRB (0.45) | THRBTGM2AKT1MAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080015280-A1 | Photosensitive Composition for Forming Optical Waveguide and Optical Waveguide | JSR CORPORATION (JP) | 2008-01-17 | — | — | US | disclosed |