SCHEMBL4872888

SCHEMBL4872888

F[C](F)C(F)(F)C(F)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11508680 0.75
SCHEMBL4350663 0.75
SCHEMBL36129 0.72
SCHEMBL108729 0.70 ALDH1A1 (0.47)
SCHEMBL11047367 0.69
SCHEMBL9797018 0.69
SCHEMBL10718379 0.69
SCHEMBL115406 0.67
SCHEMBL8587278 0.67
SCHEMBL8385682 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3325063-B1 INHALER DEVICE FOR INHALABLE LIQUIDS MEDICAL DEVELOPMENTS INTERNATIONAL LTD (AU) 2022-10-05 EP disclosed
EP-3325061-B1 INHALER DEVICE FOR INHALABLE LIQUIDS MEDICAL DEVELOPMENTS INTERNATIONAL LTD (AU) 2021-05-05 EP disclosed
CN-109803702-A INHALER DEVICE FOR INHALABLE LIQUIDS 医疗发展国际有限公司 2019-05-24 CN disclosed
CN-108348702-A INHALER DEVICE FOR INHALABLE LIQUIDS 医疗发展国际有限公司 2018-07-31 CN disclosed
CN-108348705-A Inhaler device for may be inhaled liquid 医疗发展国际有限公司 2018-07-31 CN disclosed
CN-108348703-A Inhaler device for inhalable liquids 医疗发展国际有限公司 2018-07-31 CN disclosed
CN-108348704-A Inhaler device for may be inhaled liquid 医疗发展国际有限公司 2018-07-31 CN disclosed
US-7429557-B2 Replacement solvents having improved properties and methods of using the same MAINSTREAM ENGINEERING CORPORATION (US) 2008-09-30 US disclosed
US-20060166851-A1 Replacement solvents having improved properties and methods of using the same MAINSTREAM ENGINEERING CORP. 2006-07-27 US disclosed
EP-0100788-A1 Process for preparing 1,1,2-trifluoro-2-chloroethyl difluoromethyl ether Daikin Kogyo Co., Ltd. (JP) 1984-02-22 EP disclosed