⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL171664 | 0.90 | — | — | |
| SCHEMBL25376956 | 0.88 | CXCR3 (0.37) | — | |
| SCHEMBL30562884 | 0.88 | — | — | |
| SCHEMBL13858930 | 0.88 | — | — | |
| SCHEMBL25375805 | 0.88 | CXCR3 (0.37) | — | |
| SCHEMBL25374676 | 0.88 | CXCR3 (0.37) | — | |
| SCHEMBL7218513 | 0.78 | — | — | |
| SCHEMBL11292474 | 0.69 | — | — | |
| SCHEMBL30664413 | 0.67 | — | — | |
| SCHEMBL6826368 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024105553-A1 | BICYCLIC HETEROCYCLES AND THEIR USE AS WRN INHIBITORS | NOVARTIS AG (CH) | 2024-05-23 | — | — | WO | disclosed |
| WO-2023180976-A1 | INDAZOLES AS HEMATOPOIETIC PROGENITOR KINASE 1 (HPK1) INHIBITORS AND METHODS FOR USING SAME | 1ST Biotherapeutics, Inc. (KR) | 2023-09-28 | — | — | WO | disclosed |
| WO-2023162998-A1 | COMPOSITION INCLUDING IODO COMPOUND AND USE FOR SAME | 東ソー株式会社 | 2023-08-31 | — | — | WO | disclosed |
| WO-2023096304-A1 | ISOXAZOLE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AND USE THEREOF | 한양대학교 에리카산학협력단 | 2023-06-01 | — | — | WO | disclosed |
| US-20210369716-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PARASITIC DISEASES | NOVARTIS AG (CH) | 2021-12-02 | — | — | US | disclosed |
| US-11123348-B2 | Compounds and compositions for the treatment of parasitic diseases | NOVARTIS AG (CH) | 2021-09-21 | — | — | US | disclosed |
| WO-2021008607-A1 | SUBSTITUTED 1,2,4-TRIAZOLO[4,3-A]PYRIDINE DERIVATIVE AND PREPARATION METHOD, HERBICIDAL COMPOSITION AND APPLICATION THEREOF | 青岛清原化合物有限公司 | 2021-01-21 | — | — | WO | disclosed |
| EP-3747870-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | Qingdao KingAgroot Chemical Compound Co., Ltd. (CN) | 2020-12-09 | — | — | EP | disclosed |
| EP-3712144-A1 | P2X3 AND/OR P2X2/3 RECEPTOR ANTAGONIST, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | Beijing Tide Pharmaceutical Co., Ltd. (CN) | 2020-09-23 | — | — | EP | disclosed |
| EP-3089971-B1 | COMPOUNDS AND METHODS OF USE | MEDIVATION TECH LLC (US) | 2020-07-29 | — | — | EP | disclosed |
| US-20080261923-A1 | Alkene Mimics | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-10-23 | — | — | US | disclosed |
| US-20080261923-A1 | Alkene Mimics | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-10-23 | — | — | US | disclosed |
| CN-101235052-A | Asymmetric chirality diphosphine ligand | EVONIK DEGUSSA AG (DE) | 2008-08-06 | — | — | CN | disclosed |
| US-20070299536-A1 | Collagen Mimics | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2007-12-27 | — | — | US | disclosed |
| US-7081533-B2 | Phosphorus compounds used as catalysts for asymmetric hydrogenation, hydroformylation, rearrangement, alkylation, cyclization, hydrosilation, hydrocyanation or aldol condensation | DEGUSSA AG (DE) | 2006-07-25 | — | — | US | disclosed |
| WO-2006020417-A2 | ALKENE MIMICS | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2006-02-23 | — | — | WO | disclosed |
| EP-1311517-B1 | CYCLOALIPHATIC/AROMATIC DIPHOSPHINES AND USE THEREOF IN CATALYSIS | DEGUSSA (DE) | 2004-07-14 | — | — | EP | disclosed |
| US-20040019205-A1 | Phosphorus compounds used as catalysts for asymmetric hydrogenation, hydroformylation, rearrangement, alkylation, cyclization, hydrosilation, hydrocyanation or aldol condensation | DEGUSSA AG (DE) | 2004-01-29 | — | — | US | disclosed |
| EP-1311517-A1 | CYCLOALIPHATIC/AROMATIC DIPHOSPHINES AND USE THEREOF IN CATALYSIS | Degussa AG (DE) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014330-A1 | CYCLOALIPHATIC/AROMATIC DIPHOSPHINES AND USE THEREOF IN CATALYSIS | DEGUSSA AG (DE) | 2002-02-21 | — | — | WO | disclosed |