SCHEMBL487382

SCHEMBL487382

CCCCC(CC)C[Zn]CC(CC)CCCC.OP(O)(=S)S

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.47
TDP1 Q9NUW8 2/20 0.42
CYP3A4 P08684 5/20 0.41
TSHR P16473 4/20 0.41
CA2 P00918 4/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
FDPS P14324 2/20 0.36
ATM Q13315 1/20 0.36
LMNA P02545 2/20 0.33
MEN1 O00255 1/20 0.32
USP2 O75604 1/20 0.32
TP53 P04637 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
KMT2A Q03164 1/20 0.32
HIF1A Q16665 1/20 0.32
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27698041 0.93 ALDH1A1 (0.41) ALDH1A1TDP1CYP3A4TSHRCA2
SCHEMBL20636760 0.92 ALDH1A1 (0.50) ALDH1A1TDP1CYP3A4TSHRCA2
SCHEMBL20636759 0.89 CYP3A4 (0.47) ALDH1A1TDP1CYP3A4TSHRCA2
SCHEMBL28787198 0.85 ALDH1A1 (0.44) ALDH1A1TDP1CYP3A4TSHRCA2
SCHEMBL28271519 0.84 ALDH1A1 (0.42) ALDH1A1TDP1CYP3A4TSHRCA2
SCHEMBL3334343 0.83 ALDH1A1 (0.56) ALDH1A1TDP1CYP3A4TSHRCA2
SCHEMBL27754594 0.81 ALDH1A1 (0.47) ALDH1A1TDP1CYP3A4TSHRCA2
SCHEMBL29619585 0.81 ALDH1A1 (0.47) ALDH1A1TDP1CYP3A4TSHRCA2
SCHEMBL9495722 0.79 TSHR (0.70) ALDH1A1TDP1CYP3A4TSHRCA2
SCHEMBL27296494 0.78 ALDH1A1 (0.48) ALDH1A1TDP1CYP3A4TSHRCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11390826-B2 Grease composition, machine component, and starter overrunning clutch DENSO CORPORATION (JP) 2022-07-19 US claimed
US-11390826-B2 Grease composition, machine component, and starter overrunning clutch DENSO CORPORATION (JP) 2022-07-19 US disclosed
EP-3428252-B1 GREASE COMPOSITION, MACHINE COMPONENT, AND STARTER OVERRUNNING CLUTCH DENSO CORP (JP) 2021-04-07 EP disclosed
US-20200299607-A1 GREASE COMPOSITION, MACHINE COMPONENT, AND STARTER OVERRUNNING CLUTCH DENSO CORPORATION (JP) 2020-09-24 US disclosed
US-20190085260-A1 GREASE COMPOSITION, MACHINE COMPONENT, AND STARTER OVERRUNNING CLUTCH DUPONT TORAY SPECIALTY MATERIALS KABUSHIKI KAISHA (JP) 2019-03-21 US disclosed
EP-3428252-A1 GREASE COMPOSITION, MACHINE COMPONENT, AND STARTER OVERRUNNING CLUTCH Denso Corporation (JP) 2019-01-16 EP disclosed
EP-2039745-B1 LUBE BASE OIL, LUBRICATING OIL COMPOSITION FOR INTERNAL COMBUSTION ENGINE, AND LUBRICATING OIL COMPOSITION FOR DRIVE TRANSMISSION DEVICE NIPPON OIL CORP (JP) 2013-06-05 EP disclosed
US-8105990-B2 Lube base oil, lubricating oil composition for internal combustion engine, and lubricating oil composition for drive transmission device NIPPON OIL CORPORATION (JP) 2012-01-31 US disclosed
EP-1816183-B1 DRIVING FORCE TRANSMITTING SYSTEM AND LUBRICANT COMPOSITION FOR THIS SYSTEM NIPPON OIL CORP (JP) 2011-06-22 EP disclosed
US-20100016195-A1 Lube Base Oil, Lubricating Oil Composition For Internal Combustion Engine, And Lubricating Oil Composition For Drive Transmissoin Device PETROLEUM ENERGY CENTER (JP) 2010-01-21 US disclosed
EP-2039745-A1 LUBE BASE OIL, LUBRICATING OIL COMPOSITION FOR INTERNAL COMBUSTION ENGINE, AND LUBRICATING OIL COMPOSITION FOR DRIVE TRANSMISSION DEVICE Nippon Oil Corporation (JP) 2009-03-25 EP disclosed
US-20080146474-A1 Lubricant Composition and Driving Force Transmitting System Using Same JTEKT CORPORATION (JP) 2008-06-19 US disclosed
EP-1816183-A1 LUBRICANT COMPOSITION AND DRIVING FORCE TRANSMITTING SYSTEM USING SAME Nippon Oil Corporation (JP) 2007-08-08 EP disclosed