Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 19/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14256327 | 1.00 | REN (0.55) | REN | |
| SCHEMBL14256312 | 0.84 | TACR1 (0.44) | REN | |
| SCHEMBL4873583 | 0.82 | REN (0.55) | REN | |
| SCHEMBL14256320 | 0.82 | REN (0.55) | REN | |
| SCHEMBL14256330 | 0.81 | REN (0.48) | REN | |
| SCHEMBL4868787 | 0.81 | REN (0.48) | REN | |
| SCHEMBL4873205 | 0.81 | REN (0.70) | REN | |
| SCHEMBL14256322 | 0.81 | REN (0.70) | REN | |
| SCHEMBL6620632 | 0.81 | REN (0.59) | REN | |
| SCHEMBL14256329 | 0.81 | REN (0.59) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7338965-B2 | 3,4-disubstituted, 3,5-disubstituted and 3,4,5-substituted piperidines | PHARMACIA & UPJOHN COMPANY (US) | 2008-03-04 | — | — | US | disclosed |