Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4874533 | 0.82 | PTGS1 (0.36) | CDC7CDK2PTGS1 | |
| SCHEMBL14194736 | 0.81 | PTGS1 (0.41) | CDC7CDK2PTGS1 | |
| SCHEMBL4869041 | 0.80 | PTGS1 (0.34) | CDC7CDK2PTGS1 | |
| SCHEMBL4805268 | 0.80 | PTGS2 (0.43) | CDC7CDK2PTGS1 | |
| SCHEMBL4808476 | 0.70 | PTGS1 (0.38) | CDC7CDK2PTGS1 | |
| SCHEMBL4867771 | 0.70 | PTGS1 (0.31) | PTGS1 | |
| SCHEMBL4859211 | 0.68 | MAPT (0.42) | CDC7CDK2PTGS1 | |
| SCHEMBL4805769 | 0.67 | MAPT (0.39) | CDC7CDK2PTGS1 | |
| SCHEMBL4804748 | 0.67 | PTGS1 (0.39) | CDC7CDK2PTGS1 | |
| SCHEMBL4865738 | 0.67 | PTGS2 (0.35) | CDC7CDK2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080090834-A1 | SELECTIVE AZOLE PDE10A INHIBITOR COMPOUNDS | PFIZER INC | 2008-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080090834-A1 | SELECTIVE AZOLE PDE10A INHIBITOR COMPOUNDS | PDE5A, PDE3B, PDE12 | CDC7 1474/4885CDK2 2090/4885PTGS1 527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.