Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | CBX7 | O95931 | 2/20 | 0.34 |
| ▸ | CDYL2 | Q8N8U2 | 2/20 | 0.34 |
| ▸ | CDYL | Q9Y232 | 2/20 | 0.34 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | SMO | Q99835 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4876338 | 0.93 | KCNH2 (0.39) | KCNH2HRH3TP53SMO | |
| SCHEMBL4876216 | 0.93 | KCNH2 (0.39) | KCNH2HRH3TP53 | |
| SCHEMBL4874030 | 0.93 | KCNH2 (0.39) | KCNH2HRH3TP53 | |
| SCHEMBL4875068 | 0.93 | CBX7 (0.34) | CBX7CDYL2CDYLCDY1; CDY1B | |
| SCHEMBL4868308 | 0.92 | KCNH2 (0.38) | KCNH2HRH3TP53SMO | |
| SCHEMBL4878763 | 0.92 | CBX7 (0.35) | CBX7CDYL2CDYLCDY1; CDY1BTP53 | |
| SCHEMBL4877206 | 0.91 | KCNH2 (0.34) | KCNH2HRH3CBX7CDYL2CDYL | |
| SCHEMBL4878251 | 0.91 | KCNH2 (0.38) | KCNH2HRH3TP53 | |
| SCHEMBL3938006 | 0.91 | KCNH2 (0.38) | KCNH2HRH3TP53 | |
| SCHEMBL4877273 | 0.90 | TP53 (0.40) | KCNH2HRH3CBX7CDYL2CDYL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080051384-A1 | ANTIVIRAL AGENTS | GENELABS TECHNOLOGIES, INC. | 2008-02-28 | — | — | US | disclosed |
| US-20080051384-A1 | ANTIVIRAL AGENTS | GENELABS TECHNOLOGIES, INC. | 2008-02-28 | — | — | US | disclosed |
| US-20080051384-A1 | ANTIVIRAL AGENTS | GENELABS TECHNOLOGIES, INC. | 2008-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051384-A1 | ANTIVIRAL AGENTS | EIF2AK2, MAVS, ZC3HAV1 | KCNH2 2647/4885HRH3 4258/4885CBX7 2500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.