Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5697275 | 0.84 | TSHR (0.39) | TSHRTHRBALDH1A1MAPTMAPK1 | |
| SCHEMBL2774332 | 0.81 | TSHR (0.41) | TSHRGAACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL5697272 | 0.79 | ALDH1A1 (0.43) | TSHRCYP2C19ALDH1A1 | |
| SCHEMBL980295 | 0.78 | PPARD (0.38) | TSHRTHRBALDH1A1 | |
| Nitrogen SCHEMBL28750624 | 0.78 | TSHR (0.38) | TSHRGAACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL2030812 | 0.76 | TSHR (0.39) | TSHRTHRBALDH1A1 | |
| SCHEMBL94437 | 0.75 | TSHR (0.42) | TSHRTHRBALDH1A1 | |
| SCHEMBL10768324 | 0.75 | TSHR (0.42) | TSHRTHRBALDH1A1 | |
| SCHEMBL3411978 | 0.75 | TSHR (0.37) | TSHRTHRBALDH1A1 | |
| SCHEMBL15032672 | 0.74 | MAPT (0.39) | TSHRTHRBALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8470226-B2 | Creating conduit end caps in the field | MEDHESIVES, INC. (US) | 2013-06-25 | — | — | US | claimed |
| US-7410667-B2 | Method of applying a radiation cured resin with a transparent, removable overlay | MEDHESIVES, INC. (US) | 2008-08-12 | — | — | US | claimed |
| US-20060118230-A1 | Method of applying a radiation cured resin with a transparent, removable overlay | NORTH SEA RESINS, LLC | 2006-06-08 | — | — | US | claimed |
| US-20060121148-A1 | Creating conduit end caps in the field | NORTH SEA RESINS, LLC | 2006-06-08 | — | — | US | claimed |
| US-6541537-B1 | Acrylate polymeric compositions and methods | RENAISSANCE TECHNOLOGY LLC | 2003-04-01 | — | — | US | claimed |
| CN-106574020-B | Copolymer and formed body | 株式会社可乐丽 | 2019-03-19 | — | — | CN | disclosed |
| CN-104995223-B | Copolymer and formed body | 株式会社可乐丽 | 2017-09-08 | — | — | CN | disclosed |
| CN-104995223-A | Copolymer and molded body | KURARAY CO | 2015-10-21 | — | — | CN | disclosed |
| US-8470226-B2 | Creating conduit end caps in the field | MEDHESIVES, INC. (US) | 2013-06-25 | — | — | US | disclosed |
| US-7410667-B2 | Method of applying a radiation cured resin with a transparent, removable overlay | MEDHESIVES, INC. (US) | 2008-08-12 | — | — | US | disclosed |
| US-20060121148-A1 | Creating conduit end caps in the field | NORTH SEA RESINS, LLC | 2006-06-08 | — | — | US | disclosed |
| US-20060118230-A1 | Method of applying a radiation cured resin with a transparent, removable overlay | NORTH SEA RESINS, LLC | 2006-06-08 | — | — | US | disclosed |
| US-6541537-B1 | Acrylate polymeric compositions and methods | RENAISSANCE TECHNOLOGY LLC | 2003-04-01 | — | — | US | disclosed |