Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 9/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 17/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4882511 | 0.88 | TLR7 (0.48) | TLR8TLR7 | |
| SCHEMBL4793699 | 0.86 | TLR8 (0.44) | TLR8TLR7NUDT1FBP1 | |
| SCHEMBL4879922 | 0.86 | TLR8 (0.44) | TLR8TLR7NUDT1AR | |
| SCHEMBL4793734 | 0.86 | TLR8 (0.44) | TLR8TLR7NUDT1FBP1 | |
| SCHEMBL4793789 | 0.85 | TLR8 (0.40) | TLR8TLR7NUDT1 | |
| SCHEMBL4875240 | 0.85 | TLR7 (0.46) | TLR8TLR7 | |
| SCHEMBL4792114 | 0.84 | TLR8 (0.40) | TLR8TLR7NUDT1 | |
| SCHEMBL4790923 | 0.84 | TLR8 (0.45) | TLR8TLR7NUDT1FBP1 | |
| SCHEMBL6778072 | 0.83 | TLR7 (0.41) | TLR8TLR7NUDT1 | |
| SCHEMBL6778433 | 0.82 | TLR7 (0.47) | TLR8TLR7NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513524-A4 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES CO (US) | 2008-09-03 | — | — | EP | disclosed |
| EP-1513524-A2 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M Innovative Properties Company (US) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003103584-A2 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-12-18 | — | — | WO | disclosed |