Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 10/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.42 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6783864 | 0.95 | TLR7 (0.45) | TLR7TLR8NUDT1ALDH1A1TSHR | |
| SCHEMBL6774751 | 0.92 | TLR7 (0.43) | TLR7TLR8NUDT1ALDH1A1PKM | |
| SCHEMBL6779031 | 0.91 | TLR7 (0.42) | TLR7ALDH1A1HTR1AHTR7 | |
| SCHEMBL6775204 | 0.91 | ALDH1A1 (0.45) | TLR7ALDH1A1PKMSMN1; SMN2HTR1A | |
| SCHEMBL6784344 | 0.90 | TLR7 (0.40) | TLR7TLR8ALDH1A1SMN1; SMN2HTR7 | |
| SCHEMBL6783227 | 0.89 | TLR7 (0.39) | TLR7TLR8NUDT1ALDH1A1LMNA | |
| SCHEMBL6784437 | 0.89 | TLR7 (0.41) | TLR7TLR8ALDH1A1KDM4EMAPT | |
| SCHEMBL6779938 | 0.88 | TLR7 (0.41) | TLR7TLR8ALDH1A1KDM4EPKM | |
| SCHEMBL6778425 | 0.88 | TLR7 (0.43) | TLR7TLR8NUDT1 | |
| SCHEMBL6778051 | 0.88 | TLR7 (0.46) | TLR7TLR8NUDT1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696465-B2 | INDUCING BIOSYNTHESIS OF CYTOKINES; VIRAL AND NEOPLASTIC DISEASES | 3M INNOVATIVE PROPERTIES COMPANY | 2004-02-24 | — | — | US | claimed |