SCHEMBL487520

SCHEMBL487520

[CH2]C=C(CC)CC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19409417 0.83
SCHEMBL8873743 0.83
SCHEMBL19409422 0.83
SCHEMBL8609156 0.81
SCHEMBL8609154 0.81
SCHEMBL11605970 0.76
SCHEMBL11605968 0.76
SCHEMBL11220109 0.74
SCHEMBL6950223 0.74
SCHEMBL4812475 0.74 CES2 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0605499-B1 PROCESS FOR PREPARING ENANTIOMERICALLY PURE IMIDAZO 4,5,1-jk] 1,4]-BENZODIAZEPIN-2(1H -)-THIONES JANSSEN PHARMACEUTICA NV (BE) 1997-11-12 EP claimed
US-5463049-A Process for preparing enantiomerically pure imidazo[4,5,1-JK][1,4]-benzodiazepin-2(1H)-thiones JANSSEN PHARMACEUTICA N.V. (BE) 1995-10-31 US claimed
EP-0417840-B1 Antiviral tetrahydroimidazo [1,4]-benzodiazepines JANSSEN PHARMACEUTICA NV (BE) 1994-12-07 EP claimed
US-5371079-A Administering to inhibit replication of HIV-1 in human cells JANSSEN PHARMACEUTICA N.V. (BE) 1994-12-06 US claimed
EP-0605499-A1 PROCESS FOR PREPARING ENANTIOMERICALLY PURE IMIDAZO 4,5,1-jk] 1,4]-BENZODIAZEPIN-2(1H -)-THIONES JANSSEN PHARMACEUTICA N.V. (BE) 1994-07-13 EP claimed
US-5270464-A Anti-HIV-1 tetrahydroimidazo[1,4]benzodiazepin-2-(thi) ones JANSSEN PHARMACEUTICA N.V. (BE) 1993-12-14 US claimed
WO-1993006106-A1 PROCESS FOR PREPARING ENANTIOMERICALLY PURE IMIDAZO[4,5,1-jk][1,4]-BENZODIAZEPIN-2(1H^_)-THIONES JANSSEN PHARMACEUTICA N.V. (BE) 1993-04-01 WO claimed
EP-0534539-A1 Process for preparing enantiomerically pure imidazo[4,5,1-jk]-[1,4]-benzodiazepin-2(1H)-thiones JANSSEN PHARMACEUTICA N.V. (BE) 1993-03-31 EP claimed
EP-0491751-A1 ANTIVIRAL TETRAHYDROIMIDAZO 1,4]BENZODIAZEPINES JANSSEN PHARMACEUTICA N.V. (BE) 1992-07-01 EP claimed
WO-1991004255-A1 ANTIVIRAL TETRAHYDROIMIDAZO[1,4]BENZODIAZEPINES JANSSEN PHARMACEUTICA N.V. (BE) 1991-04-04 WO claimed
EP-0417840-A1 Antiviral tetrahydroimidazo [1,4]-benzodiazepines JANSSEN PHARMACEUTICA N.V. (BE) 1991-03-20 EP claimed
EP-4305020-A1 MALONAMIDES AND THEIR USE AS HERBICIDES BASF SE (DE) 2024-01-17 EP disclosed
US-10799441-B2 Skin treatments containing pyrroloquinoline quinone (PQQ) esters and methods of preparation and use thereof PCR TECHNOLOGY HOLDINGS, LC (US) 2020-10-13 US disclosed
US-20190040367-A1 STILBENOID PRENYLTRANSFERASES FROM PLANTS Arkansas State University - Jonesboro 2019-02-07 US disclosed
US-10081748-B2 Methods for thickening hydrophobic liquids with amphiphilic esters THE RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) 2018-09-25 US disclosed
US-4374137-A ANALGESIC, ANTICONVULSANT, HYPOTENSIVE, DIURETIC HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1983-02-15 US disclosed
US-4355037-A ANALGESICS HOECHST-ROUSSEL PHARMACEUTICALS (US) 1982-10-19 US disclosed
US-4208523-A NARCOTICS, ANALGESICS STERLING DRUG INC. (US) 1980-06-17 US disclosed
US-4141893-A Decahydrocyclopent[c]azepines ELI LILLY AND COMPANY (US) 1979-02-27 US disclosed
US-4141894-A ANALGESICS, ANTAGONISTS ELI LILLY AND COMPANY (US) 1979-02-27 US disclosed