Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylamide SCHEMBL29120843 | 0.85 | TSHR (0.44) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL21829112 | 0.83 | TSHR (0.63) | TSHRHPGDALDH1A1TP53HIF1A | |
| Chloromethane SCHEMBL2315463 | 0.82 | TSHR (0.37) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL10936951 | 0.80 | TSHR (0.83) | TSHRHPGDALDH1A1TP53HIF1A | |
| Acrylic Acid SCHEMBL6888124 | 0.79 | TSHR (0.58) | TSHRHPGDALDH1A1TP53HIF1A | |
| Methacrylic Acid SCHEMBL1085237 | 0.79 | TSHR (0.73) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL2942280 | 0.78 | TSHR (0.66) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL4619099 | 0.77 | TSHR (0.70) | TSHRHPGDALDH1A1TP53HIF1A | |
| Methacrylic Acid SCHEMBL28812158 | 0.77 | TSHR (0.70) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL932598 | 0.77 | TSHR (0.70) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8822585-B2 | Aqueous dispersion of polymeric particles | ROHM AND HAAS COMPANY (US) | 2014-09-02 | — | — | US | disclosed |
| US-20080058457-A1 | Aqueous dispersion of polymeric particles | ROHM AND HAAS COMPANY | 2008-03-06 | — | — | US | disclosed |