Chloromethane

Chloromethane

SCHEMBL2315463

C=C(C)C(=O)NC(C)C.C=CC(=O)OCCN(C)C.CCl

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.37
HPGD P15428 1/20 0.36
ALDH1A1 P00352 4/20 0.36
TP53 P04637 3/20 0.36
HIF1A Q16665 3/20 0.36
CYP3A4 P08684 3/20 0.36
HSD17B10 Q99714 1/20 0.36
CHRM2 P08172 1/20 0.35
CHRM4 P08173 1/20 0.35
CHRM5 P08912 1/20 0.35
CHRM1 P11229 1/20 0.35
CHRNB2 P17787 1/20 0.35
CHRM3 P20309 1/20 0.35
CHRNA4 P43681 1/20 0.35
THRB P10828 1/20 0.35
DNM1 Q05193 1/20 0.33
TGFBR1 P36897 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C19 P33261 1/20 0.32
BLM P54132 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4875634 0.82 TSHR (0.58) TSHRHPGDALDH1A1TP53HIF1A
Chloromethane SCHEMBL127030 0.81 TSHR (0.52) TSHRHPGDALDH1A1TP53HIF1A
Chloromethane SCHEMBL28118762 0.80 TSHR (0.50) TSHRHPGDALDH1A1TP53HIF1A
Chloromethane SCHEMBL28391697 0.80 TSHR (0.50) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL7089812 0.80 TSHR (0.42) TSHRHPGDALDH1A1TP53HIF1A
Methacrylic Acid SCHEMBL4594665 0.78 TSHR (0.46) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL15115 0.78 TSHR (0.56) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL5397321 0.77 ALDH1A1 (0.47) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL7516575 0.77 TSHR (0.44) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL1538397 0.77 TSHR (0.44) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2352805-B1 METHOD OF CONTROLLING GAS HYDRATES IN FLUID SYSTEMS NALCO CO (US) 2014-07-30 EP claimed
US-20100099814-A1 METHOD OF CONTROLLING GAS HYDRATES IN FLUID SYSTEMS HARBISON-FISCHER, INC. 2010-04-22 US claimed
US-9550935-B2 Method of controlling gas hydrates in fluid systems NALCO COMPANY (US) 2017-01-24 US disclosed
US-20150119299-A1 METHOD OF CONTROLLING GAS HYDRATES IN FLUID SYSTEMS US SYNTHETIC CORPORATION 2015-04-30 US disclosed
US-8921478-B2 Method of controlling gas hydrates in fluid systems NALCO COMPANY (US) 2014-12-30 US disclosed
EP-2352805-B1 METHOD OF CONTROLLING GAS HYDRATES IN FLUID SYSTEMS NALCO CO (US) 2014-07-30 EP disclosed
EP-2352805-A1 METHOD OF CONTROLLING GAS HYDRATES IN FLUID SYSTEMS Nalco Company (US) 2011-08-10 EP disclosed
US-20100099814-A1 METHOD OF CONTROLLING GAS HYDRATES IN FLUID SYSTEMS HARBISON-FISCHER, INC. 2010-04-22 US disclosed
WO-2010045523-A1 METHOD OF CONTROLLING GAS HYDRATES IN FLUID SYSTEMS NALCO COMPANY (US) 2010-04-22 WO disclosed