Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 12/20 | 0.53 |
| ▸ | CHRNA4 | P43681 | 12/20 | 0.53 |
| ▸ | CHRNB4 | P30926 | 9/20 | 0.53 |
| ▸ | CHRNA3 | P32297 | 9/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL654514 | 0.83 | HRH3 (0.59) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL654513 | 0.83 | HRH3 (0.59) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL27594011 | 0.83 | HRH3 (0.59) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL650412 | 0.82 | HRH3 (0.58) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL650240 | 0.82 | HRH3 (0.58) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL3580915 | 0.82 | CHRNB2 (0.49) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL6782940 | 0.82 | CHRNB2 (0.49) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL3579848 | 0.82 | CHRNB2 (0.49) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL7688783 | 0.82 | CHRNB2 (0.49) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL3572734 | 0.76 | CHRNB2 (0.55) | CHRNB2CHRNA4CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7319106-B2 | Diazabicyclic central nervous system active agents | ABBOTT LABORATORIES (US) | 2008-01-15 | — | — | US | claimed |