Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 4/20 | 0.53 |
| ▸ | HMGCR | P04035 | 2/20 | 0.53 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | SELP | P16109 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26623145 | 0.91 | DNM1 (0.55) | PTPN7HMGCRDNM1MEN1KMT2A | |
| SCHEMBL2206547 | 0.91 | DNM1 (0.55) | PTPN7HMGCRDNM1MEN1KMT2A | |
| SCHEMBL2205033 | 0.91 | DNM1 (0.62) | PTPN7HMGCRDNM1MEN1KMT2A | |
| SCHEMBL2200542 | 0.91 | DNM1 (0.62) | PTPN7HMGCRDNM1MEN1KMT2A | |
| SCHEMBL2200462 | 0.91 | DNM1 (0.62) | PTPN7HMGCRDNM1MEN1KMT2A | |
| SCHEMBL2208525 | 0.91 | DNM1 (0.62) | PTPN7HMGCRDNM1MEN1KMT2A | |
| SCHEMBL2205868 | 0.91 | DNM1 (0.62) | PTPN7HMGCRDNM1MEN1KMT2A | |
| SCHEMBL2205799 | 0.91 | DNM1 (0.62) | PTPN7HMGCRDNM1MEN1KMT2A | |
| SCHEMBL21294356 | 0.91 | DNM1 (0.55) | PTPN7HMGCRDNM1MEN1KMT2A | |
| SCHEMBL17965814 | 0.90 | HMGCR (0.61) | PTPN7HMGCRTSHRSELP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080296513-A1 | Integrating ultraviolet exposure detection devices | SEGAN INDUSTRIES, INC. | 2008-12-04 | — | — | US | disclosed |
| US-20070053856-A1 | Integrating ultraviolet exposure detection devices | SEGAN INDUSTRIES, INC. | 2007-03-08 | — | — | US | disclosed |
| US-20060054838-A1 | Integrating ultraviolet exposure detection devices | RIBI HANS O | 2006-03-16 | — | — | US | disclosed |
| WO-2005036109-A2 | INTEGRATING ULTRAVIOLET EXPOSURE DETECTION DEVICES | SEGAN INDUSTRIES, INC. (US) | 2005-04-21 | — | — | WO | disclosed |
| US-20030226978-A1 | Integrating ultraviolet exposure detection devices | SEGAN INDUSTRIES | 2003-12-11 | — | — | US | disclosed |