Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 16/20 | 0.58 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4987469 | 0.95 | AOC3 (0.57) | AOC3PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL4873931 | 0.94 | AOC3 (0.50) | AOC3RORC | |
| SCHEMBL5496093 | 0.93 | AOC3 (0.59) | AOC3PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL5551608 | 0.92 | AOC3 (0.60) | AOC3RORC | |
| SCHEMBL4988932 | 0.92 | AOC3 (0.56) | AOC3RORC | |
| SCHEMBL4873660 | 0.92 | AOC3 (0.61) | AOC3RORC | |
| SCHEMBL5550423 | 0.91 | AOC3 (0.54) | AOC3PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL4876188 | 0.91 | AOC3 (0.48) | AOC3RORC | |
| SCHEMBL4866140 | 0.89 | AOC3 (0.46) | AOC3RORC | |
| SCHEMBL4982443 | 0.89 | AOC3 (0.58) | AOC3PIK3CDPIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7442715-B2 | Thiazole derivatives | ASTELLAS PHARMA INC. (JP) | 2008-10-28 | — | — | US | disclosed |
| US-20060276521-A1 | Thiazole derivatives | ASTELLAS PHARMA INC. (JP) | 2006-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276521-A1 | Thiazole derivatives | VCAM1, ICAM1, TXNL1 | AOC3 782/4885PIK3CD 4519/4885PIK3CA 4514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.