Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.37 |
| ▸ | CES1 | P23141 | 2/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 6/20 | 0.35 |
| ▸ | NPC1 | O15118 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28350465 | 0.85 | TSHR (0.37) | TSHRCES1CES2ALDH1A1SMN1; SMN2 | |
| SCHEMBL7801403 | 0.84 | TSHR (0.36) | TSHRCES1CES2ALDH1A1SMN1; SMN2 | |
| SCHEMBL16566541 | 0.81 | LMNA (0.41) | TSHRALDH1A1SMN1; SMN2HSD17B10ALOX15 | |
| SCHEMBL30448716 | 0.76 | LMNA (0.36) | TSHRCES1CES2ALDH1A1SMN1; SMN2 | |
| SCHEMBL28442226 | 0.76 | NPC1 (0.40) | TSHRCES1CES2ALDH1A1SMN1; SMN2 | |
| SCHEMBL10711342 | 0.74 | CES1 (0.34) | TSHRCES1CES2ALDH1A1SMN1; SMN2 | |
| SCHEMBL5170532 | 0.72 | POLB (0.35) | TSHRHSD17B10KMT2AMAPTMAPK1 | |
| SCHEMBL28737646 | 0.71 | CES1 (0.35) | TSHRCES1CES2ALDH1A1SMN1; SMN2 | |
| SCHEMBL28359782 | 0.68 | LMNA (0.37) | TSHRCES1CES2ALDH1A1SMN1; SMN2 | |
| SCHEMBL10959754 | 0.68 | NPC1 (0.40) | TSHRCES1CES2ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080160118-A1 | TREATMENT OF SKIN WITH COSMETIC AND DERMATOLOGICAL PREPARATIONS CONTAINING EXTRACTS FROM SEEDS OF PLANTS OF THE GENUS ADENANTHERA | MOSER PHILIPPE | 2008-07-03 | — | — | US | disclosed |
| US-4165397-A | Repair of glass laminates | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1979-08-21 | — | — | US | disclosed |