Sugi Predict

Sugi Predict / Compounds / SCHEMBL4877010

SCHEMBL4877010

SCHEMBL4877010

CCCCCCCCCC(=O)CCc1ccc(O)c(OC)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ CYP3A4 P08684 5/20 1.00
▸ CYP2C8 P10632 5/20 1.00
▸ CYP2C9 P11712 5/20 1.00
▸ CYP2B6 P20813 5/20 1.00
▸ CYP2C19 P33261 5/20 1.00
▸ CYP1A2 P05177 4/20 1.00
▸ ALOX5 P09917 3/20 0.73
▸ HTR1A P08908 5/20 0.72
▸ CYP2D6 P10635 3/20 0.72
▸ CYP2A6 P11509 3/20 0.72
▸ LTA4H P09960 3/20 0.72
▸ CYP2E1 P05181 2/20 0.72
▸ TRPV1 Q8NER1 3/20 0.72
▸ OR51E2 Q9H255 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29711594 1.00 CYP3A4 (1.00) CYP3A4CYP2C8CYP2C9CYP2B6CYP2C19
SCHEMBL30417499 1.00 CYP3A4 (1.00) CYP3A4CYP2C8CYP2C9CYP2B6CYP2C19
SCHEMBL4881362 1.00 CYP3A4 (1.00) CYP3A4CYP2C8CYP2C9CYP2B6CYP2C19
SCHEMBL29371372 1.00 CYP3A4 (1.00) CYP3A4CYP2C8CYP2C9CYP2B6CYP2C19
SCHEMBL29801887 1.00 CYP3A4 (1.00) CYP3A4CYP2C8CYP2C9CYP2B6CYP2C19
SCHEMBL29805047 1.00 CYP3A4 (1.00) CYP3A4CYP2C8CYP2C9CYP2B6CYP2C19
SCHEMBL971599 1.00 CYP3A4 (1.00) CYP3A4CYP2C8CYP2C9CYP2B6CYP2C19
SCHEMBL4883880 1.00 CYP3A4 (1.00) CYP3A4CYP2C8CYP2C9CYP2B6CYP2C19
SCHEMBL4885822 1.00 CYP3A4 (1.00) CYP3A4CYP2C8CYP2C9CYP2B6CYP2C19
SCHEMBL17546694 0.99 CYP3A4 (0.97) CYP3A4CYP2C8CYP2C9CYP2B6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11964935-B2 Gingerol derivative having inhibitory activity against biofilm formation and pharmaceutical composition comprising same as effective ingredient for preventing or treating biofilm-caused infection symptom KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION, SEJONG CAMPUS (KR) 2024-04-23 — — US disclosed
US-20200283364-A1 GINGEROL DERIVATIVE HAVING INHIBITORY ACTIVITY AGAINST BIOFILM FORMATION AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS EFFECTIVE INGREDIENT FOR PREVENTING OR TREATING BIOFILM-CAUSED INFECTION SYMPTOM KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION, SEJONG CAMPUS (KR) 2020-09-10 — — US disclosed
WO-2019017709-A1 GINGEROL DERIVATIVE HAVING INHIBITORY ACTIVITY AGAINST BIOFILM FORMATION AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS EFFECTIVE INGREDIENT FOR PREVENTING OR TREATING BIOFILM-CAUSED INFECTION SYMPTOM 고려대학교 세종산학협력단 2019-01-24 — — WO disclosed
EP-3281620-A1 PHOTOPROTECTIVE COMPOSITION BASED ON A 2-ALKOXY-4-ALKYL KETONE PHENOL COMPOUND; USE OF SAID COMPOUND FOR INCREASING THE SUN PROTECTION FACTOR L'OREAL (FR) 2018-02-14 — — EP disclosed
US-9358192-B2 Photoprotective composition based on a 2-alkoxy-4-alkyl ketone phenol compound; use of said compound for increasing the sun protection factor L'OREAL (FR) 2016-06-07 — — US disclosed
US-9358192-B2 Photoprotective composition based on a 2-alkoxy-4-alkyl ketone phenol compound; use of said compound for increasing the sun protection factor L'OREAL (FR) 2016-06-07 — — US disclosed
US-20150064225-A1 PHOTOPROTECTIVE COMPOSITION BASED ON A 2-ALKOXY-4-ALKYL KETONE PHENOL COMPOUND; USE OF SAID COMPOUND FOR INCREASING THE SUN PROTECTION FACTOR OREAL (FR) 2015-03-05 — — US disclosed
US-20150064225-A1 PHOTOPROTECTIVE COMPOSITION BASED ON A 2-ALKOXY-4-ALKYL KETONE PHENOL COMPOUND; USE OF SAID COMPOUND FOR INCREASING THE SUN PROTECTION FACTOR OREAL (FR) 2015-03-05 — — US disclosed
US-8765101-B2 Photoprotective composition based on a 2-alkoxy-4-alkyl ketone phenol compound; use of said compound for increasing the sun protection factor L'OREAL (FR) 2014-07-01 — — US disclosed
US-8765101-B2 Photoprotective composition based on a 2-alkoxy-4-alkyl ketone phenol compound; use of said compound for increasing the sun protection factor L'OREAL (FR) 2014-07-01 — — US disclosed
US-20120263768-A1 PHOTOPROTECTIVE COMPOSITION BASED ON A 2-ALKOXY-4-ALKYL KETONE PHENOL COMPOUND; USE OF SAID COMPOUND FOR INCREASING THE SUN PROTECTION FACTOR L'OREAL (FR) 2012-10-18 — — US disclosed
US-20120263768-A1 PHOTOPROTECTIVE COMPOSITION BASED ON A 2-ALKOXY-4-ALKYL KETONE PHENOL COMPOUND; USE OF SAID COMPOUND FOR INCREASING THE SUN PROTECTION FACTOR L'OREAL (FR) 2012-10-18 — — US disclosed
WO-2011042358-A1 PHOTOPROTECTIVE COMPOSITION BASED ON A 2-ALKOXY-4-ALKYL KETONE PHENOL COMPOUND; USE OF SAID COMPOUND FOR INCREASING THE SUN PROTECTION FACTOR L'OREAL (FR) 2011-04-14 — — WO disclosed
WO-2011039444-A2 COMPOSITION, USE, AND PRESERVATION METHOD L'OREAL (FR) 2011-04-07 — — WO disclosed
US-7728043-B2 Methods for treatment of beta-amyloid protein-induced ocular disease KIM DARRICK S H L 2010-06-01 — — US disclosed
US-20080038386-A1 Use of a liquid cooling sensate to provide a pungent, warming or tingling sensate composition MOZA ASHOK K 2008-02-14 — — US disclosed
US-20070003641-A1 Synergistic pharmaceutical compositions useful in prevention and treatment of beta-amyloid protein-induced disease KIM DARRICK S H 2007-01-04 — — US disclosed
EP-1056700-B1 MEDICINAL USES OF PHENYLALKANOLS AND DERIVATES ZINGOTX PTY LTD (AU) 2006-09-20 — — EP disclosed
US-6518315-B1 Treatment or prophylaxis of diseases by the inhibition of platelet aggregation THE UNIVERSITY OF SYDNEY (AU) 2003-02-11 — — US disclosed
US-4623665-A PARADOLS LEE SANG S 1986-11-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150064225-A1 PHOTOPROTECTIVE COMPOSITION BASED ON A 2-ALKOXY-4-ALKYL KETONE PHENOL COMPOUND; USE OF SAID COMPOUND FOR INCREASING THE SUN PROTECTION FACTOR AHR, TYR, CUTA CYP3A4 707/4885CYP2C8 1367/4885CYP2C9 805/4885
US-20070003641-A1 Synergistic pharmaceutical compositions useful in prevention and treatment of beta-amyloid protein-induced disease APP, BACE1, GSAP CYP3A4 3043/4885CYP2C8 3793/4885CYP2C9 4211/4885
US-20200283364-A1 GINGEROL DERIVATIVE HAVING INHIBITORY ACTIVITY AGAINST BIOFILM FORMATION AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS EFFECTIVE INGREDIENT FOR PREVENTING OR TREATING BIOFILM-CAUSED INFECTION SYMPTOM LSS, F2R, CFTR CYP3A4 508/4885CYP2C8 956/4885CYP2C9 881/4885
US-20120263768-A1 PHOTOPROTECTIVE COMPOSITION BASED ON A 2-ALKOXY-4-ALKYL KETONE PHENOL COMPOUND; USE OF SAID COMPOUND FOR INCREASING THE SUN PROTECTION FACTOR AHR, TYR, CUTA CYP3A4 707/4885CYP2C8 1367/4885CYP2C9 805/4885
US-11964935-B2 Gingerol derivative having inhibitory activity against biofilm formation and pharmaceutical composition comprising same as effective ingredient for preventing or treating biofilm-caused infection symptom LSS, F2R, CFTR CYP3A4 508/4885CYP2C8 956/4885CYP2C9 881/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.