Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GGT1 | P19440 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8647754 | 0.81 | KDM4E (0.76) | KDM4EHSD17B10HPGDMAPTALDH1A1 | |
| SCHEMBL28611217 | 0.79 | AKT1 (0.50) | KDM4EHSD17B10HPGDMAPTAKT1 | |
| SCHEMBL27891498 | 0.77 | SLC6A3 (0.63) | KDM4EHSD17B10HPGDMAPTAKT1 | |
| SCHEMBL752535 | 0.76 | KDM4E (0.73) | KDM4EHSD17B10HPGDMAPTALDH1A1 | |
| SCHEMBL29378503 | 0.76 | KDM4E (0.73) | KDM4EHSD17B10HPGDMAPTALDH1A1 | |
| SCHEMBL10347642 | 0.76 | AKT1 (0.61) | KDM4EHSD17B10HPGDMAPTAKT1 | |
| SCHEMBL38652294 | 0.76 | ABCG2 (0.63) | KDM4EHSD17B10HPGDMAPTALDH1A1 | |
| SCHEMBL31561740 | 0.76 | ABCG2 (0.64) | ABCG2MAOBSMN1; SMN2 | |
| SCHEMBL7469828 | 0.76 | ABCG2 (0.64) | ABCG2MAOBSMN1; SMN2 | |
| SCHEMBL8728695 | 0.75 | KDM4E (0.53) | KDM4EHSD17B10HPGDMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080217803-A1 | Method of Molding a Hydrodynamic Pressure Producuing Part | NTN CORPORATION (JP) | 2008-09-11 | — | — | US | disclosed |