Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 3/20 | 0.44 |
| ▸ | ADK | P55263 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 3/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 3/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14519076 | 0.82 | GSK3B (0.53) | PARP1GSK3BCYP2A6AHRMEN1 | |
| SCHEMBL22457398 | 0.77 | AHR (0.56) | GSK3BCYP2A6AHRMEN1MAPT | |
| SCHEMBL5636554 | 0.76 | KIF11 (0.47) | PARP1GSK3BAHRMEN1MAPT | |
| SCHEMBL16107082 | 0.75 | GSK3B (0.56) | PARP1GSK3BADKBCHEKIF11 | |
| 2-Phenyl-1H-Indole-3-Carbaldehyde SCHEMBL1429713 | 0.75 | ESR1 (0.55) | GSK3BAHRMEN1MAPTKMT2A | |
| SCHEMBL14519056 | 0.74 | PIK3CA (0.51) | GSK3BCYP2A6AHRMEN1MAPT | |
| SCHEMBL18943573 | 0.74 | BCHE (0.46) | PARP1GSK3BADKBCHEAHR | |
| SCHEMBL12694210 | 0.73 | TRIM24 (0.43) | PARP1CYP2A6ERN1MAPTIMPDH2 | |
| SCHEMBL29030265 | 0.72 | GAA (0.48) | PARP1GSK3BADKBCHEMEN1 | |
| SCHEMBL5634757 | 0.72 | GSK3B (0.46) | GSK3BAHRMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8716491-B2 | Benzimidazolium dyes and their use as fluorescent chemosensors | NEW YORK UNIVERSITY (US) | 2014-05-06 | — | — | US | disclosed |
| US-20080160521-A1 | BENZIMIDAZOLIUM DYES AND THEIR USE AS FLUORESCENT CHEMOSENSORS | NEW YORK UNIVERSITY (US) | 2008-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080160521-A1 | BENZIMIDAZOLIUM DYES AND THEIR USE AS FLUORESCENT CHEMOSENSORS | IK, C9, CBR3 | PARP1 435/4885GSK3B 4820/4885ADK 4779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.